Merck
All Photos(2)

A8456

Sigma-Aldrich

4-(2-氨乙基)苯磺酰氟 盐酸盐

≥97.0% (HPLC)

Synonym(s):
AEBSF
Empirical Formula (Hill Notation):
C8H10FNO2S · HCl
CAS Number:
Molecular Weight:
239.69
Beilstein:
7604627
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

生物来源

synthetic (organic)

质量水平

300

测定

≥97.0% (HPLC)

形式

powder

mp

183-191  °C

溶解性

H2O: 50 mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.)

储存温度

−20°C

SMILES string

FS(C1=CC=C(CCN)C=C1)(=O)=O.[H]Cl

InChI

1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H

InChI key

WRDABNWSWOHGMS-UHFFFAOYSA-N

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包装

25, 100, 500 mg in poly bottle

应用

建议使用浓度为 0.1 至 1mM。

生化/生理作用

不可逆的丝氨酸蛋白酶抑制剂。抑制常数与 PMSF 和 DFP 的抑制常数相似。AEBSF 可以抑制胰蛋白酶、糜蛋白酶、纤溶酶、激肽释放酶和凝血酶。作为 PMSF 和 DFP 的替代物,AEBSF 的毒性更低、水溶性和水溶液稳定性更好。AEBSF 已用于细胞培养,使用浓度可达 0.25mM。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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