Merck

E1769

Sigma-Aldrich

N-(3-二甲基氨基丙基)-N'-乙基碳二亚胺 盐酸盐

BioXtra

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别名:
N-乙基-N′ -(3-二甲基氨基丙基)碳二亚胺 盐酸盐, EDAC, EDC, EDC 盐酸盐, WSC 盐酸盐
Empirical Formula (Hill Notation):
C8H17N3 · HCl
CAS号:
分子量:
191.70
Beilstein:
5764110
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.25

产品线

BioXtra

质量水平

形式

powder

杂质

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

灼烧残渣

≤0.1%

mp

110-115 °C (lit.)

溶解性

H2O: 0.5 M, clear to very slightly hazy, colorless to very faintly yellow

痕量阴离子

sulfate (SO42-): ≤0.05%

痕量阳离子

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

储存温度

−20°C

SMILES string

Cl.CCN=C=NCCCN(C)C

InChI

1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H

InChI key

FPQQSJJWHUJYPU-UHFFFAOYSA-N

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此商品
E6383341006E7750
EDAC, Hydrochloride EDAC HCl is a water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis.

Sigma-Aldrich

341006

EDAC,盐酸盐

-
form

powder

form

crystalline

form

solid

form

powder

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

impurities

-

impurities

-

impurities

-

mp

110-115 °C (lit.)

mp

110-115 °C (lit.)

mp

-

mp

110-115 °C (lit.)

solubility

H2O: 0.5 M, clear to very slightly hazy, colorless to very faintly yellow

solubility

H2O: ≤100 mg/mL

solubility

aqueous buffer: 2-5 mg/mL, water: 2-5 mg/mL

solubility

H2O: ≤100 mg/mL

cation traces

Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

cation traces

-

cation traces

-

cation traces

-

应用

N-(3-二甲基氨基丙基)-N′-乙基碳二亚胺盐酸盐已用于:
  • 来自福尔马林固定石蜡包埋(FFPE)组织的小核糖核酸(RNA)种类的后固定和交联,用于荧光原位杂交(FISH)和免疫荧光(IF)信号
  • 纳米纤维基质与小鼠肺组织提取物的交联
  • 底物XNA寡核苷酸的激活

生化/生理作用

水溶性缩合试剂。EDAC通常用作与伯胺进行酰胺键合的羧基活化剂。另外,它能与磷酸基团反应。其已用于例如肽合成、将蛋白质与核酸交联、以及免疫缀合物的制备。通常,EDAC在不含缓冲剂的pH范围4.0-6.0的条件下使用。特别是,应避免使用胺和羧酸盐缓冲液。

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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