Merck
所有图片(1)

X100PC

Sigma-Aldrich

Triton X-100

peroxide- and carbonyl-free

别名:
4-(1,1,3,3-四甲基丁基)苯基-聚乙二醇, 叔辛基苯氧基聚乙烯乙氧基乙醇, 聚乙二醇叔辛基苯基醚
线性分子式:
t-Oct-C6H4-(OCH2CH2)xOH, x= 9-10
CAS号:
Beilstein:
2315025
MDL编号:
PubChem化学物质编号:

质量水平

200

描述

non-ionic

形式

liquid

分子量

micellar avg mol wt 80,000
average mol wt 625

包装

ampule of 5, 5x5, 10x5 mL

聚集数

100-155

CMC

0.2-0.9 mM (20-25°C)

转变温度

cloud point 65 °C
pour point ~7 °C

溶解性

water: soluble

HLB

13.5

SMILES string

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

InChI key

HNLXNOZHXNSSPN-UHFFFAOYSA-N

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一般描述

Triton X-100 是一种常见的非离子表面活性剂和乳化剂,常用在生化应用中溶解蛋白质。它是相对温和的洗涤剂,非变性,据报道,在许多参考文献中被用作常规添加剂。它用于裂解细胞、提取蛋白质和细胞器。它还可以增强活细胞可渗透性,便于转染。

应用

0·3% Triton X-100 TBS 溶液已用于免疫染色前视网膜的透化。 0.5% Triton X-100 已用于星形胶质细胞裂解。

包装

5, 5×5, 10×5 mL in ampule
氩气保护下安瓿包装。

生化/生理作用

广泛使用的非离子表面活性剂,用于在温和的非变性条件下进行膜恢复。

法律信息

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(F)

483.8 °F

闪点(C)

251 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

分析证书

请输入批号搜索分析证书(COA)。

原产地证书 (CofO)

请输入批号搜索原产地证书(COO)。

Quantitative ex vivo detection of rodent retinal ganglion cells by immunolabeling Brn-3b.
Experimental Eye Research, 79(1), 131-140 (2004)
Cytotoxicity of bilirubin for human fibroblasts and rat astrocytes in culture. Effect of the ratio of bilirubin to serum albumin.
Chuniaud L, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 256(2), 103-114 (1996)
Adeno-associated virus mediated SOD gene therapy protects the retinal ganglion cells from chronic intraocular pressure elevation induced injury via attenuating oxidative stress and improving mitochondrial dysfunction in a rat model.
American Journal of Translational Research, 8(2), 799-799 (2016)
The size, shape, and hydration of nonionic surfactant micelles. Triton X-100.
Robson RJ and Dennis EA
The Journal of Physical Chemistry, 81, 1075-1078 (1977)
Friederike Pfeiffer et al.
Acta neuropathologica, 122(5), 601-614 (2011-10-11)
In experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), loss of the blood-brain barrier (BBB) tight junction (TJ) protein claudin-3 correlates with immune cell infiltration into the CNS and BBB leakiness. Here we show that sealing BBB

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