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47608

Sigma-Aldrich

甲醛 溶液

for molecular biology, BioReagent, ≥36.0% in H2O (T)

别名:
福尔马林
线性分子式:
HCHO
CAS号:
分子量:
30.03
Beilstein:
1209228
MDL编号:
PubChem化学物质编号:
NACRES:
NA.52

质量水平

100

等级

for molecular biology

蒸汽密度

1.03 (vs air)

蒸汽压

52 mmHg ( 37 °C)

产品线

BioReagent

测定

36.0-38.0% (aldehyde method)

形式

liquid

自燃温度

572 °F

包含

~10% methanol as stabilizer

浓度

≥36.0% in H2O (T)

应用

electrophoresis: suitable

杂质

≤0.03% free acid (as HCOOH)

灼烧残渣

≤0.05% (as SO4)

pH

2.8-4.0

密度

1.09 g/mL at 20 °C
1.09 g/mL at 25 °C (lit.)

痕量阴离子

chloride (Cl-): ≤10 mg/kg
sulfate (SO42-): ≤20 mg/kg

痕量阳离子

Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Na: ≤100 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤1 mg/mL

λ

2 M in H2O

紫外吸收

λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01

适用性

in accordance for electrophoresis of RNA in agarose gels

储存温度

room temp

SMILES string

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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一般描述

甲醛是一种分子生物学试剂,将其掺入琼脂糖凝胶,可用于在电泳过程中使RNA变性。

应用

适用于
  • RNA分子的变性和分离
  • 抗菌治疗
  • 固定细胞

注意

可能含有沉淀(多聚甲醛)

原理

甲醛能够破坏RNA的二级结构,并帮助实现基于电荷迁移的RNA种类分离和鉴定。

警示用语:

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

靶器官

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK Germany

WGK 3

闪点(F)

133.0 °F - closed cup

闪点(C)

56.11 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

分析证书

原产地证书 (CofO)

Jin Qian et al.
Virology, 474, 10-18 (2014-12-03)
Interferon-induced transmembrane (IFITM) proteins inhibit the entry of a large number of viruses. Not surprisingly, many viruses are refractory to this inhibition. In this study, we report that different strains of HIV and SIV are inhibited by human IFITM proteins...
Y Jiang et al.
Oncogene, 34(50), 6079-6091 (2015-03-10)
Epstein-Barr virus (EBV) causes human lymphoid malignancies, and the EBV product latent membrane protein 1 (LMP1) has been identified as an oncogene in epithelial carcinomas such as nasopharyngeal carcinoma (NPC). EBV can epigenetically reprogram lymphocyte-specific processes and induce cell immortalization....
Dannis G van Vuurden et al.
Neuro-oncology, 16(7), 946-959 (2014-01-29)
Glial brain tumors cause considerable mortality and morbidity in children and adults. Innovative targets for therapy are needed to improve survival and reduce long-term sequelae. The aim of this study was to find a candidate tumor-promoting protein, abundantly expressed in...
Oliver Wicht et al.
Journal of virology, 88(14), 7952-7961 (2014-05-09)
Isolation of porcine epidemic diarrhea coronavirus (PEDV) from clinical material in cell culture requires supplementation of trypsin. This may relate to the confinement of PEDV natural infection to the protease-rich small intestine of pigs. Our study focused on the role...
John N Griffin et al.
PLoS genetics, 11(3), e1005018-e1005018 (2015-03-11)
The production of ribosomes is ubiquitous and fundamental to life. As such, it is surprising that defects in ribosome biogenesis underlie a growing number of symptomatically distinct inherited disorders, collectively called ribosomopathies. We previously determined that the nucleolar protein, NOL11...

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