Merck

60010

Sigma-Aldrich

山柰酚

≥97.0% (HPLC)

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别名:
3,4′,5,7-四羟基黄酮, 3,5,7-三羟基-2-(4-羟基苯基)-4 H -1-苯并吡喃-4-酮, 萝卜素
经验公式(希尔记法):
C15H10O6
CAS号:
分子量:
286.24
Beilstein:
304401
MDL编号:
PubChem化学物质编号:
NACRES:
NA.47

检测方案

≥97.0% (HPLC)

杂质

≤12% water

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

SMILES string

Oc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2

InChI

1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H

InChI key

IYRMWMYZSQPJKC-UHFFFAOYSA-N

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此商品
K013396353PHL89235
vibrant-m

60010

山柰酚

vibrant-m

K0133

山柰酚

vibrant-m

96353

山柰酚

vibrant-m

PHL89235

山柰酚

assay

≥97.0% (HPLC)

assay

≥90% (HPLC)

assay

≥99.0% (HPLC)

assay

≥95.0% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

impurities

≤12% water

impurities

-

impurities

-

impurities

-

Gene Information

human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), CYP2C9(1559), GSK3A(2931)
mouse ... Hexa(15211)

Gene Information

human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), CYP2C9(1559), GSK3A(2931)
mouse ... Hexa(15211)

Gene Information

-

Gene Information

-

一般描述

山柰酚是一种多酚类抗氧化剂,广泛存在于蔬菜和水果中。它具有二苯基丙烷结构。在许多植物中,它以糖苷形式存在,即山柰酚-3-O-葡糖苷。

应用

山柰酚可用于:
  • 测试其对成骨细胞增殖、迁移及小鼠成骨前细胞系(MC3T3-E1 细胞)中分化的影响
  • 用作玉米烯酮(ZEA)诱导的氧化应激和 HEPG2 细胞中的细胞凋亡的抗氧化剂和肝保护剂
  • 用作一种神经保护剂,以对抗氯化镉(CdCl2)诱导的大鼠海马损伤和记忆缺陷
  • 用作抗炎剂,与芹菜素一起对患有膝关节骨性关节炎的雄性大鼠进行干细胞治疗

锑的显色剂在低 ppm 范围内 ,镓和铟的显色剂在亚 ppm 范围内。

生化/生理作用

山柰酚基于其二苯基丙烷基团而具有疏水性。它具有抗炎作用和抗氧化特性,并且可调节促炎酶的活性。山柰酚是一种化学预防剂,对细胞活性具有保护作用。它可调节与细胞凋亡、血管生成、转移和炎症相关的信号转导途径的几个关键要素。
有效的破骨细胞骨吸收抑制剂。认为该作用归因于山奈酚的抗氧化和雌激素活性。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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山奈酚3-β-D-吡喃葡萄糖苷 primary reference standard

04500585

山奈酚3-β-D-吡喃葡萄糖苷

片素 ≥98% (TLC), powder

Sigma-Aldrich

L9283

片素

杨梅黄素 ≥96.0%, crystalline

Sigma-Aldrich

M6760

杨梅黄素

杨梅黄素 analytical standard

Supelco

72576

杨梅黄素

异鼠李素 United States Pharmacopeia (USP) Reference Standard

USP

1351800

异鼠李素

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Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

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