Merck
所有图片(1)

69453

Sigma-Aldrich

L-高半胱氨酸

≥98.0% (NT)

别名:
L-高半胱氨酸(盐酸盐)
线性分子式:
HSCH2CH2CH(NH2)COOH
CAS号:
分子量:
135.18
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.32

质量水平

100

测定

≥98.0% (NT)

形式

powder

旋光性

[α]/D 25.5±1.5°, c = 1 in 1 M HCl

颜色

white

mp

263-265 °C

application(s)

cell analysis

相关疾病

Alzheimer′s disease

储存温度

−20°C

SMILES string

N[C@@H](CCS)C(O)=O

InChI

1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1

InChI key

FFFHZYDWPBMWHY-VKHMYHEASA-N

一般描述

L-高半胱氨酸已用于诊断高半胱氨酸尿症。

应用

L-高半胱氨酸已用作细胞培养基中的补充成分。

生化/生理作用

血浆和组织中同型半胱氨酸水平的升高与阿尔茨海默′s病以及健康老年人的脑萎缩有关。同型半胱氨酸水平升高是由于维生素B缺乏,特别是叶酸、B6和B12维生素,它们是参与同型半胱氨酸代谢的酶的辅助因子。

包装

无底玻璃瓶。内容物在插入式融锥内。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

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原产地证书 (CofO)

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更多文件

Quotes and Ordering

Arpita Basu et al.
Atherosclerosis, 236(1), 188-195 (2014-07-27)
Plasma total homocysteine (tHcy) has been positively associated with carotid intima-media thickness (IMT) in non-diabetic populations and in a few cross-sectional studies of diabetic patients. We investigated cross-sectional and prospective associations of a single measure of tHcy with common and
Assessment of homocysteine status
Refsum H, et al.
Journal of inherited metabolic disease, 20(2), 286-294 (1997)
K Mehlig et al.
Heart (British Cardiac Society), 99(23), 1761-1765 (2013-09-10)
An elevated level of total plasma homocysteine (tHcy) has been associated with risk of coronary heart disease (CHD). The level of tHcy is affected by lifestyle, in addition to genetic predisposition. The methylene tetrahydrofolate reductase (MTHFR) 677C>T polymorphism (rs1801133) is
SAGE open medicine, 286054-286054 (2014)
Rajendra P Shukla et al.
Advanced healthcare materials, 8(15), e1900462-e1900462 (2019-06-27)
The antipsychotic clozapine is the most effective medication available for schizophrenia and it is the only antipsychotic with a known efficacious clinical range. However, it is dramatically underutilized due to the inability to test clozapine blood levels in finger-pricked patients'

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