Merck
All Photos(7)

A1653

Sigma-Aldrich

白蛋白 来源于人类血清

lyophilized powder, ≥96% (agarose gel electrophoresis)

Synonym(s):
HSA
CAS Number:
EC 号:
MDL编号:
eCl@ss:
42010201
NACRES:
NA.25

生物来源

human

质量水平

300

测定

≥96% (agarose gel electrophoresis)

形式

lyophilized powder

分子量

monomer calculated mol wt 66478 Da

technique(s)

ELISA: suitable
tissue culture: suitable
western blot: suitable

杂质

HIV I and HIVII, HCV and HBsAg, tested negative

溶解性

H2O: soluble 50 mg/mL

UniProt登记号

储存温度

2-8°C

Gene Information

human ... ALB(213)

Looking for similar products? Visit Product Comparison Guide

一般描述

Albumin (ALB) constitutes 25% of the proteins produced by the liver.[1] It is a protein of a single polypeptide chain with a thiol group.[2] The ALB gene is mapped to human 4q13.3.[3]

应用

白蛋白用于测试其对头孢托仑对耐青霉素的肺炎链球菌的体外杀菌活性的影响。[4]
它已在临床上用于严重和经常危及生命的情况,例如由于外伤、烧伤和手术引起的休克和失血。[5]
Albumin from human serum has been used:
  • in cyclophilin isomerase assay[6]
  • as a component in blocking solution for immunogold quantification of amino acids and proteins in complex subcellular compartments[7]
  • in G-pseudotyped HIV (PHIV) assay mixture to study its effect on GSK364735 antiviral potency[8]

包装

500 mg in poly bottle
1, 5, 10, 50, 100 g in poly bottle

生化/生理作用

血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白,对调节血液的胶体渗透压至关重要。研究还发现白蛋白可结合外源物质,特别是药物(例如布洛芬、华法林),并强烈影响其药代动力学。导致白蛋白氧化还原状态变化的氧化应激对其生理功能具有广泛的影响。
Albumin serves as a protein repository and functions as a binding and transport protein. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This prevents the loss of substance through excretion.[9] Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia.[1]

质量

其余大部分为球蛋白

其他说明

更多信息参见人血清白蛋白

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Product Information Sheet

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service