Merck
  • A2129
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A2129

Sigma-Aldrich

γ-氨基丁酸

≥99%

Synonym(s):
]γ-氨酪酸, 3-羧丙胺, 4-氨基丁酸, GABA, 哌啶酸, 氨酪酸
Linear Formula:
NH2(CH2)3COOH
CAS Number:
Molecular Weight:
103.12
Beilstein:
906818
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥99%

形式

powder or crystals

储存条件

(Tightly closed. Dry.)

颜色

colorless

mp

195 °C (dec.) (lit.)

溶解性

water: 50 mg/mL, clear, colorless

SMILES string

NCCCC(O)=O

InChI

1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)

InChI key

BTCSSZJGUNDROE-UHFFFAOYSA-N

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γ-Aminobutyric acid ≥99%

Sigma-Aldrich

A2129

γ-氨基丁酸

γ-Aminobutyric acid certified reference material, TraceCERT®

Supelco

43811

γ-氨基丁酸

γ-Aminobutyric acid analytical standard

Supelco

03835

γ-氨基丁酸

γ-Aminobutyric acid phyproof® Reference Substance

PHL83415

γ-氨基丁酸

assay

≥99%

assay

-

assay

≥97.0% (HPLC)

assay

≥98.0% (HPLC)

form

powder or crystals

form

-

form

-

form

crystals

storage condition

(Tightly closed. Dry.)

storage condition

under inert gas

storage condition

-

storage condition

-

color

colorless

color

-

color

-

color

-

solubility

water: 50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

-

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

-

一般描述

γ-氨基丁酸 (GABA) 是一种非氨基蛋白质,存在于植物、动物和微生物中。GABA已应用于制药和食品工业,作为奶酪、烧酒、金白龙茶和精油成分。
研究领域:神经科学

应用

γ-氨基丁酸(GABA)用于:
  • 制备GABA-BSA(牛血清蛋白)-GA(戊二醛)复合物,用于GABA免疫染色对照。
  • 核磁共振(MRS)高分子抑制检测。
  • GABA肠内给药,降低管腔内液体分泌

生化/生理作用

GABA(γ-氨基丁酸)是一种氨基酸,作为中枢神经系统中的抑制性神经递质,在某些外周组织中也可用作神经调节剂。其可与GABAA受体结合,抑制信号接收神经元活性。GABAA受体能够在神经细胞细胞膜形成通道。一旦和GABA结合,受体被激活,允许带负电的分子,比如氯离子通过通道,进入细胞。这导致细胞兴奋性降低。
GABA 能神经元参与肌肉松弛、抗焦虑治疗、镇静和麻醉。GABA 还可影响心率和血压。
GABA可以改善大脑中的血浆浓度、生长激素和蛋白质合成。它还在降低人体血压方面发挥作用。GABA 是一种有效的降压药、利尿剂和抗糖尿病 药。它还可调节血脂水平和疼痛感。
大脑中的主要抑制性神经递质;GABAA 和 GABAB 受体激动剂;增加 Cl 的传导性。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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