A4474

L-精氨酸

• Synonym(s): (S)-2-氨基-5-胍基戊酸
• Linear Formula: H₂NC(=NH)NH(CH₂)₃CH(NH₂)CO₂H
• CAS Number: 74-79-3
• Molecular Weight: 174.20
• Beilstein: 1725413
• EC 号: 200-811-1
• MDL编号: MFCD00002635
• eCl@ss: 32160406
• PubChem化学物质编号: 57653850
• NACRES: NA.26

Properties

• 生物来源: non-animal source
• 质量水平: 400
• 测定: >98.5%
• 形式: crystalline powder
• manufacturer/tradename: Ajinomoto
• technique(s): cell culture | mammalian: suitable
• 杂质: endotoxin, heavy metals, trace metals, residual solvents, tested
• mp: 222 °C (dec.) (lit.)
• 溶解性: H₂O: 100 mg/mL
• 适用性: suitable for manufacturing use
• application(s): pharmaceutical (small molecule)
• SMILES string: N[C@@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
• InChI key: ODKSFYDXXFIFQN-BYPYZUCNSA-N
• Gene Information: human ... NOS1(4842) , NOS2(4843) ; rat ... Ppm1a(24666)

Description

一般描述

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Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

应用

L-精氨酸是一种非必需氨基酸。 它用作细胞培养基组分，用于治疗性重组蛋白和单克隆抗体的商业生物制造。

生化/生理作用

一氧化氮合成酶的底物，可转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• 储存分类代码: 13 - Non Combustible Solids
• WGK: WGK 1
• 闪点(F): Not applicable
• 闪点(C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)