Merck
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A5282

Sigma-Aldrich

DL-2-氨基-5-膦酰戊酸

solid

Synonym(s):
5-膦酰基-DL-正缬氨酸, DL-2-氨基-5-膦酰基缬草酸, AP-5, APV
Empirical Formula (Hill Notation):
C5H12NO5P
CAS Number:
Molecular Weight:
197.13
Beilstein:
2446389
MDL编号:
PubChem化学物质编号:
NACRES:
NA.32

形式

solid

颜色

white

溶解性

0.1 M NaOH: 4 mg/mL
H2O: 5.6 mg/mL
organic solvents: insoluble

SMILES string

NC(CCCP(O)(O)=O)C(O)=O

InChI

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)

InChI key

VOROEQBFPPIACJ-UHFFFAOYSA-N

Gene Information

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应用

DL-2-氨基-5-膦酰戊酸已用于:
  • N-甲基-D-天冬氨酸(NMDA)介导突触灭活
  • 用于生长培养基用于抑制神经元网络的电活性
  • 用于分离N-甲基-D-天冬氨酸受体(NMDAR)或α-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体(AMPAR)介导电流
  • 溶于双蒸水中,与朊蛋白(PrPC)比较其NMDA拮抗作用

包装

10, 25, 50, 100 mg in glass bottle

生化/生理作用

镇痉;有效的选择性NMDA受体拮抗剂。

注意

吸湿

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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