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A7469

Sigma-Aldrich

L-丙氨酸

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

别名:
L-α-氨基丙酸, (S)-2-氨基丙酸
Empirical Formula (Hill Notation):
C3H7NO2
CAS号:
分子量:
89.09
Beilstein:
1720248
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26

质量水平

200

生物来源

non-animal source

机构/方法

meets EP testing specifications
meets USP testing specifications

产品线

BioXtra

测定

98.5-101.0%

形式

powder

应用

cell culture | mammalian: suitable
peptide synthesis: suitable

杂质

endotoxin, tested

颜色

white

溶解性

H2O: 100 mg/mL

特色行业

Pharmaceutical (small molecule)

SMILES string

C[C@H](N)C(O)=O

InChI

1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1

InChI key

QNAYBMKLOCPYGJ-REOHCLBHSA-N

Gene Information

human ... CA1(759) , CA2(760)

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应用

作为培养基组分,L-丙氨酸已被用于组织培养技术。它已被用作成年小鼠角质形成细胞生长的培养基组分。

包装

10 mg in glass bottle
25, 100 g in poly bottle
1 kg in poly bottle

生化/生理作用

L-丙氨酸是一种非必需氨基酸,在肌肉中高度集中。它是葡萄糖-丙氨酸循环中的关键参与者,该循环可以将肌肉中的丙酮酸和谷氨酸转移至肝脏中。一旦进入肝脏,葡萄糖可从丙酮酸再生并返回肌肉,而谷氨酸最终参与尿素循环以形成尿素。葡萄糖-丙氨酸循环有助于保持肌肉中的ATP以促进肌肉收缩,同时糖异生的能量负担将转移至肝脏。丙氨酸可抑制丙酮酸激酶,以调节糖异生和糖酵解过程,从而便于在饥饿期间维持葡萄糖稳态。丙氨酸可预防肝脏自噬。丙氨酸的形成是谷氨酸和丙酮酸的氨基转移的结果。

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

原产地证书 (CofO)

Alanine and Glutamine Synthesis and Release from Skeletal
Muscle
ALAN J. GARBER
The Journal of Biological Chemistry, 251(3) (1976)
A primary culture technique of adult retina for regeneration studies on adult CNS neurons
Alexandra Kretz
Nature Protocols, 131-140 (2007)
Amino acids: metabolism, functions, and nutrition
Guoyao Wu
Amino Acids, 37(1) (2009)
Serial Cultivation of Primary Adult Murine Keratinocytes
Richard P. Redvers and Pritinder Kaur
Methods in Molecular Biology, 15-22 (2005)
Muscle alanine synthesis and hepatic gluconeogenesis
Snell K
Biochemical Society Transactions, 8(2), 205-213 (1980)

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