- C4163
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生物来源
bovine eye (lens)
质量水平
测定
≥70% (biuret)
形式
lyophilized powder
technique(s)
cell culture | mammalian: suitable
储存温度
−20°C
Gene Information
bovine ... CRYAA(281718) , CRYAB(281719)
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This Item | F1392 | F2253 | F6750 |
|---|---|---|---|
| biological source bovine eye (lens) | biological source - | biological source synthetic | biological source - |
| assay ≥70% (biuret) | assay ≥70% | assay ≥70% (HPLC) | assay 73-79% (fluorimetric) |
| form lyophilized powder | form powder | form powder | form powder |
| technique(s) cell culture | mammalian: suitable | technique(s) electrophoresis: suitable | technique(s) - | technique(s) - |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. - | UniProt accession no. - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
应用
α-晶状体蛋白是一种晶状体蛋白，含有两个同源亚基：αA- 和 αB-晶状体蛋白。α-晶状体蛋白表现出类似伴侣的活性，并在保持镜片透明度方面发挥重要作用。已经注意到，在大鼠的糖尿病条件下，α-晶状体蛋白的伴侣活性下降。研究表明，膳食抗氧化剂姜黄素可以防止这种分子伴侣活性的丢失。
生化/生理作用
α-晶状体蛋白是一种小型热休克蛋白，具有类似伴侣的活性，可防止蛋白质在体外聚集。α-晶状体蛋白基因中的点突变被认为是导致遗传性白内障发展的原因。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(F)
Not applicable
闪点(C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Certificate of Analysis
Enter Lot Number to search for Certificate of Analysis (COA).
Certificate of Origin
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