Merck
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文件

C5360

SAFC

L-半胱氨酸

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别名:
(R)-2-氨基-3-巯基丙酸
线性分子式:
HSCH2CH(NH2)CO2H
CAS号:
52-90-4
分子量:
121.16
Beilstein:
1721408
EC 号:
200-158-2
MDL编号:
MFCD00064306
eCl@ss:
32160406
NACRES:
NA.26

生物来源

non-animal source

形式

crystalline powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

杂质

endotoxin, heavy metals, trace metals, tested

mp

240 °C (dec.) (lit.)

溶解性

H2O: 25 mg/mL

适用性

suitable for manufacturing use

异质活性

cytotoxicity, tested

SMILES string

N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

InChI key

XUJNEKJLAYXESH-REOHCLBHSA-N

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此商品
95437778672W326305
L-Cysteine

SAFC

C5360

L-半胱氨酸

L-Cysteine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

95437

L-半胱氨酸

L-Cysteine produced by Wacker Chemie AG, Burghausen, Germany, ≥98.0%

Sigma-Aldrich

778672

L-半胱氨酸

L-Cysteine ≥97%, FG

Sigma-Aldrich

W326305

L-半胱氨酸

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

impurities

endotoxin, heavy metals, trace metals, tested

impurities

-

impurities

≤0.5% ninhidrin positive substances (each), ≤10 ppm heavy metals, ≤300 ppm ammonium

impurities

-

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

solubility

H2O: 25 mg/mL

solubility

-

solubility

-

solubility

H2O: 25 mg/mL

biological source

non-animal source

biological source

-

biological source

-

biological source

-

一般描述

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我们用于生物制药加工的SAFC® 系列优质原料经过严格的质量控制流程，配合记录文件和技术专长帮助我们的客户达到M-Clarity 计划规定的要求。

M-Clarity计划

我们全面的上游工艺化学品系列不仅为生物制药生产商提供生产传统和创新治疗药物所需的优质原料，而且帮助他们更快地将产品投放市场并简化监管问题。 请相信我们能够为您带来透明的供应链和可靠的全球采购能力，以最佳的法规支持和服务简化您的产品认证。

应用

L-半胱氨酸是一种非必需氨基酸。 它常被用作细胞培养基成分，用于治疗性重组蛋白和单克隆抗体的商业化生物制造。

生化/生理作用

NMDA 谷氨酸受体激动剂。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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示例

T1503
货号
-
25G
包装规格/数量

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MMYOMAG-74K-13

1000309185

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L-Arginine

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A4474

L-精氨酸

L-Cysteine hydrochloride monohydrate from non-animal source, suitable for cell culture, meets EP, USP testing specifications

Sigma-Aldrich

C6852

L-半胱氨酸 盐酸盐 一水合物

D-Cysteine ≥99% (RT)

Sigma-Aldrich

30095

D-半胱氨酸

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T4321

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Nicholas Kwiatkowski et al.
Nature, 511(7511), 616-620 (2014-07-22)
Tumour oncogenes include transcription factors that co-opt the general transcriptional machinery to sustain the oncogenic state, but direct pharmacological inhibition of transcription factors has so far proven difficult. However, the transcriptional machinery contains various enzymatic cofactors that can be targeted
Eun Young Park et al.
Journal of agricultural and food chemistry, 62(26), 6183-6189 (2014-06-01)
The present study examined the impact of the supplementation of glutathione (GSH), γ-L-glutamyl-L-cysteinyl-glycine, on human blood GSH levels. Healthy human volunteers were orally supplemented with GSH (50 mg/kg body weight). Venous blood was collected from the cubital vein before and
Takeshi Annoura et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(5), 2158-2170 (2014-02-11)
The 10 Plasmodium 6-Cys proteins have critical roles throughout parasite development and are targets for antimalaria vaccination strategies. We analyzed the conserved 6-cysteine domain of this family and show that only the last 4 positionally conserved cysteine residues are diagnostic
Georg K A Hochberg et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), E1562-E1570 (2014-04-09)
Mammalian small heat-shock proteins (sHSPs) are molecular chaperones that form polydisperse and dynamic complexes with target proteins, serving as a first line of defense in preventing their aggregation into either amorphous deposits or amyloid fibrils. Their apparently broad target specificity
John Gilchrist et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(51), E5016-E5024 (2013-12-04)
Voltage-gated sodium (Nav) channels are embedded in a multicomponent membrane signaling complex that plays a crucial role in cellular excitability. Although the mechanism remains unclear, β-subunits modify Nav channel function and cause debilitating disorders when mutated. While investigating whether β-subunits
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膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

Chromatograms

application for HPLC

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