所有图片(1)

C5735

L -胱氨酸

所有图片(1)

别名:

(R,R)-3,3′-亚二硫基二(2-丙氨酸)

线性分子式:

[-SCH₂CH(NH₂)CO₂H]₂

CAS号:

56-89-3

分子量:

240.30

Beilstein:

1728094

EC 号:

200-296-3

MDL编号:

MFCD00064228

PubChem化学物质编号:

24892581

NACRES:

NA.26

质量水平

400

生物来源

non-animal source

测定

≥98.5%

形式

powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

杂质

endotoxin, tested

mp

>240 °C (dec.) (lit.)

溶解性

1 M HCl: 100 mg/mL

适用性

suitable for manufacturing use

application(s)

pharmaceutical (small molecule)

SMILES string

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

LEVWYRKDKASIDU-IMJSIDKUSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

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原产地证书 (CofO)

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Quotes and Ordering

Bulk Quote-Order Product

Targeting allosteric disulphide bonds in cancer.

Philip J Hogg

Nature reviews. Cancer, 13(6), 425-431 (2013-05-11)

Protein action in nature is generally controlled by the amount of protein produced and by chemical modification of the protein, and both are often perturbed in cancer. The amino acid side chains and the peptide and disulphide bonds that bind

Evaluation of the taurine concentrations in dog plasma and aqueous humour: a pilot study.

Serge-George Rosolen et al.

Advances in experimental medicine and biology, 775, 145-154 (2013-02-09)

In the 70s, the amino acid taurine was found essential for photoreceptor survival. Recently, we found that taurine depletion can also trigger retinal ganglion cell degeneration both in vitro and in vivo. Therefore, evaluation of taurine levels could be a

The pathogenesis of cystinosis: mechanisms beyond cystine accumulation.

Martijn J Wilmer et al.

American journal of physiology. Renal physiology, 299(5), F905-F916 (2010-09-10)

Renal proximal tubules are highly sensitive to ischemic and toxic insults and are affected in diverse genetic disorders, of which nephropathic cystinosis is the most common. The disease is caused by mutations in the CTNS gene, encoding the lysosomal cystine

The cyclic cystine ladder in θ-defensins is important for structure and stability, but not antibacterial activity.

Anne C Conibear et al.

The Journal of biological chemistry, 288(15), 10830-10840 (2013-02-23)

θ-Defensins are ribosomally synthesized cyclic peptides found in the leukocytes of some primate species and have promising applications as antimicrobial agents and scaffolds for peptide drugs. The cyclic cystine ladder motif, comprising a cyclic peptide backbone and three parallel disulfide

The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.

Jan Lewerenz et al.

Antioxidants & redox signaling, 18(5), 522-555 (2012-06-07)

The antiporter system x(c)(-) imports the amino acid cystine, the oxidized form of cysteine, into cells with a 1:1 counter-transport of glutamate. It is composed of a light chain, xCT, and a heavy chain, 4F2 heavy chain (4F2hc), and, thus

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