Merck
所有图片(5)

文件

D9628

Sigma-Aldrich

左旋多巴

≥98% (TLC)

所有图片(5)
别名:
3-(3,4-二羟基苯基)-L-丙氨酸, 3-羟基-L-酪氨酸, L-DOPA, 左多巴
线性分子式:
(HO)2C6H3CH2CH(NH2)CO2H
CAS号:
59-92-7
分子量:
197.19
Beilstein:
2215169
EC 号:
200-445-2
MDL编号:
MFCD00002598
eCl@ss:
32160406
PubChem化学物质编号:
24277914
NACRES:
NA.32

质量水平

200

检测方案

≥98% (TLC)

形式

powder

颜色

white to off-white

mp

276-278 °C (lit.)

application(s)

peptide synthesis

储存温度

room temp

SMILES string

N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O

InChI

1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

InChI key

WTDRDQBEARUVNC-LURJTMIESA-N

Gene Information

human ... DRD1(1812) , DRD2(1813) , DRD3(1814) , DRD4(1815) , DRD5(1816)
mouse ... DRD1(13488) , DRD2(13489) , DRD3(13490) , DRD4(13491) , DRD5(13492)
rat ... DRD1(24316) , DRD2(24318) , DRD3(29238) , DRD4(25432) , DRD5(25195)

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此商品
72816L0400000PHR1271
3,4-Dihydroxy-L-phenylalanine ≥98% (TLC)

Sigma-Aldrich

D9628

左旋多巴

3,4-Dihydroxy-L-phenylalanine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

72816

左旋多巴

Levodopa European Pharmacopoeia (EP) Reference Standard

L0400000

左多巴

Levodopa Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1271

左多巴

form

powder

form

-

form

-

form

-

color

white to off-white

color

-

color

-

color

-

mp

276-278 °C (lit.)

mp

276-278 °C (lit.)

mp

276-278 °C (lit.)

mp

276-278 °C (lit.)

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

application(s)

peptide synthesis

application(s)

food and beverages

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

应用

3,4-二羟基-L-苯丙氨酸或L-DOPA被用来对黑色素细胞染色。它还被用于研究其对帕金森病 果蝇 模型的影响。

生化/生理作用

3,4-二羟基-L-苯丙氨酸或L-DOPA是多巴胺直接前体的一种天然异构体，它能穿过血脑屏障。它被应用于治疗帕金森疾病 ，是酪氨酸羟化酶的产物。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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熊果苷

Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson?s disease
Malgorzata Pokrzywa
PLoS ONE (2017)
Primary culture of human face skin melanocytes for the study of hyperpigmentation
Cytotechnology, 66(6) (2014)
Alan J. Sinclair, John E. Morley, Bruno Vellas
Pathy's Principles and Practice of Geriatric Medicine (2012)
Nicolas Morin et al.
Experimental neurology, 256, 105-116 (2013-01-31)
The treatment of motor symptoms of Parkinson disease (PD) with the dopamine (DA) precursor, l-3,4-dihydroxyphenylalanine (l-DOPA) introduced 50years ago still remains a very effective medication. However, involuntary movements termed l-DOPA-induced dyskinesias (LID) appear in the vast majority of PD patients
Molly J Crockett et al.
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An aversion to harming others is a core component of human morality and is disturbed in antisocial behavior. Deficient harm aversion may underlie instrumental and reactive aggression, which both feature in psychopathy. Past work has highlighted monoaminergic influences on aggression
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