Merck
所有图片(5)

D9628

Sigma-Aldrich

左旋多巴

≥98% (TLC)

别名:
3-羟基-L-酪氨酸, 左多巴, L-DOPA, 3-(3,4-二羟基苯基)-L-丙氨酸
线性分子式:
(HO)2C6H3CH2CH(NH2)CO2H
CAS号:
分子量:
197.19
Beilstein:
2215169
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.32

质量水平

200

测定

≥98% (TLC)

形式

powder

颜色

white to off-white

mp

276-278 °C (lit.)

application(s)

peptide synthesis

储存温度

room temp

SMILES string

N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O

InChI

1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

InChI key

WTDRDQBEARUVNC-LURJTMIESA-N

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应用

3,4-二羟基-L-苯丙氨酸或L-DOPA被用来对黑色素细胞染色。它还被用于研究其对帕金森病 果蝇 模型的影响。

包装

5, 25, 100, 500 g in poly bottle

生化/生理作用

3,4-二羟基-L-苯丙氨酸或L-DOPA是多巴胺直接前体的一种天然异构体,它能穿过血脑屏障。它被应用于治疗帕金森疾病 ,是酪氨酸羟化酶的产物。

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

分析证书

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原产地证书 (CofO)

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Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson?s disease
Malgorzata Pokrzywa
PLoS ONE (2017)
Alan J. Sinclair, John E. Morley, Bruno Vellas
Pathy's Principles and Practice of Geriatric Medicine (2012)
Primary culture of human face skin melanocytes for the study of hyperpigmentation
Cytotechnology, 66(6) (2014)
Molly J Crockett et al.
Current biology : CB, 25(14), 1852-1859 (2015-07-07)
An aversion to harming others is a core component of human morality and is disturbed in antisocial behavior. Deficient harm aversion may underlie instrumental and reactive aggression, which both feature in psychopathy. Past work has highlighted monoaminergic influences on aggression
Nicolas Morin et al.
Experimental neurology, 256, 105-116 (2013-01-31)
The treatment of motor symptoms of Parkinson disease (PD) with the dopamine (DA) precursor, l-3,4-dihydroxyphenylalanine (l-DOPA) introduced 50years ago still remains a very effective medication. However, involuntary movements termed l-DOPA-induced dyskinesias (LID) appear in the vast majority of PD patients

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