F6879

铁蛋白 来源于人类脾脏

Type V, 10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide

• CAS Number: 9007-73-2
• MDL编号: MFCD00081593
• NACRES: NA.61

Properties

• 生物来源: human spleen
• 质量水平: 100
• sterility: sterile-filtered
• 类型: Type V
• 形式: liquid
• 包装: vial of 2 μg
• 浓度: 10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide
• UniProt登记号: P02792; P02794
• 储存温度: 2-8°C
• Gene Information: human ... FTH1(2495) , FTL(2512)

Description

应用

Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.

包装

1 vial

5 vials

生化/生理作用

A ubiquitous iron storage protein that plays a key role in iron metabolism. It serves as an intracellular iron reserve (particularly in spleen, liver, intestinal mucosa, and bone marrow) and functions in iron detoxification. Studies have shown that ferritin iron incorporation is mediated by a ferroxidase activity associated with ferritin H subunits and a nucleation center associated with ferritin L subunits. Release of iron from ferritin has an essential role in iron-dependent lipid peroxidation and may contribute to free radical-induced cell damage in vivo. Therefore, by binding iron, ferritin may function as an antioxidant.

Safety Information

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(F): Not applicable
• 闪点(C): Not applicable