Merck
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F8758

Sigma-Aldrich

叶酸

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥97%

Synonym(s):
戊基单谷氨酸, N-4-[(2-氨基-4-氧代-1,4-二氢-6-喋啶)甲氨基苯甲酰基]-L-谷氨酸, PteGlu, 维生素 M
Empirical Formula (Hill Notation):
C19H19N7O6
CAS Number:
Molecular Weight:
441.40
Beilstein:
100781
EC 号:
MDL编号:
eCl@ss:
34058014
PubChem化学物质编号:
NACRES:
NA.75

生物来源

synthetic

质量水平

300

产品线

BioReagent

测定

≥97%

形式

powder

分子量

Mw 441.40 g/mol

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

颜色

dark yellow

溶解性

1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, faintly yellow to dark yellow-orange

储存温度

room temp

SMILES string

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChI key

OVBPIULPVIDEAO-LBPRGKRZSA-N

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一般描述

叶酸(FA)/蝶酰单谷氨酸 有助于阻断神经管缺陷(NTD)。

应用

叶酸已被用于:
  • 研究维生素和氨基酸对杂交瘤生长和单克隆抗体生成的影响
  • 用于细胞和治疗
  • 使用CRISPR/Cas基因编辑方法进行穿孔素基因打靶

包装

5, 25 g in glass bottle

生化/生理作用

叶酸的营养输送形式。叶酸及其衍生物是细胞内一碳代谢的必需介质。

其他说明

Scripps Center for Metabolomics(斯克里普斯代谢组学中心)独立生成的串联质谱数据,可以PDF格式查看或下载。 F8758.pdf 经测试的代谢物被收录在Scripps代谢组学中心METLIN代谢物数据库中。更多信息请见sigma.com/metlin。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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