Merck

G1251

Sigma-Aldrich

L-谷氨酸

ReagentPlus®, ≥99% (HPLC)

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别名:
(S)-2-氨基戊二酸, Glu
线性分子式:
HO2CCH2CH2CH(NH2)CO2H
CAS号:
分子量:
147.13
Beilstein:
1723801
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26

Agency

suitable for SM 5210

产品线

ReagentPlus®

检测方案

≥99% (HPLC)

形式

powder

technique(s)

microbiological culture: suitable

颜色

white to off-white

mp

205 °C (dec.) (lit.)

溶解性

1 M HCl: soluble 100 mg/mL

密度

1.54 g/cm3 at 20 °C

痕量阳离子

C: 40.4-41.2%
N: 9.2-9.8%

SMILES string

N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

InChI key

WHUUTDBJXJRKMK-VKHMYHEASA-N

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此商品
49449954361294976
L-Glutamic acid ReagentPlus®, ≥99% (HPLC)

Sigma-Aldrich

G1251

L-谷氨酸

-
L-Glutamic acid BioUltra, ≥99.5% (NT)

Sigma-Aldrich

49449

L-谷氨酸

Premium Grade
L-Glutamic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

95436

L-谷氨酸

-
Glutamic acid United States Pharmacopeia (USP) Reference Standard

USP

1294976

谷氨酸

-
assay

≥99% (HPLC)

assay

≥99.5% (NT)

assay

-

assay

-

form

powder

form

powder

form

-

form

crystalline

technique(s)

microbiological culture: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable

color

white to off-white

color

white

color

-

color

-

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

应用

L-谷氨酸已被用于增强内源性乙酰胆碱的溢出。它已被用作肉腐 莓实假单胞菌 72生长培养基中的补充剂。

生化/生理作用

一种兴奋性氨基酸神经递质,是谷氨酸受体(代谢型、红藻氨酸盐、NMDA和AMPA)的所有亚型的激动剂。
谷氨酸或谷氨酸盐(谷氨酸的盐形式)可作为神经递质起作用,并且还可作为其他神经递质如γ-氨基丁酸的前体。谷氨酸在许多控制生长、繁殖、维持和免疫的代谢途径中也起着关键作用。它被转化为α-酮戊二酸,其是TCA(三羧酸)循环的关键组分,也是核酸和某些氨基酸生物合成的前体。在细胞中,谷氨酰胺通过酶谷氨酰胺酶转化为谷氨酸。
谷氨酰胺作为快速分裂细胞(包括淋巴细胞、肠细胞、巨噬细胞和肿瘤)的能量来源。谷氨酰胺通过细胞mTOR(雷帕霉素的哺乳动物靶标)信号转导介导蛋白质的周转。其还已报到可与细胞凋亡的抑制有关。
一种兴奋性氨基酸神经递质,为谷氨酸盐受体所有亚型(代谢型红藻氨酸、NMDA 和 AMPA)的激动剂。

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Glutamic acid, twenty years later.
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