G5417

甘氨酸

• Synonym(s): 氨基乙酸, 甘氨酸
• Linear Formula: NH₂CH₂COOH
• CAS Number: 56-40-6
• Molecular Weight: 75.07
• Beilstein: 635782
• EC 号: 200-272-2
• MDL编号: MFCD00008131
• eCl@ss: 32160406
• PubChem化学物质编号: 24895210
• NACRES: NA.25

Properties

• 生物来源: non-animal source
• 质量水平: 400
• 测定: ≥98.5%
• 形式: crystalline powder
• manufacturer/tradename: Ajinomoto
• technique(s): cell culture | mammalian: suitable
• 杂质: endotoxin, heavy metals, trace metals, residual solvents, tested
• pH值（酸碱度）: 5.9-6.4
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• 溶解性: H₂O: 100 mg/mL
• 紫外吸收: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: -0.006; λ: 280 nm A_max: ≤0.04; λ: 280 nm A_max: -0.003
• 适用性: suitable for manufacturing use
• application(s): pharmaceutical (small molecule)
• 异质活性: cytotoxicity, tested
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Gene Information: rat ... Grin2a(24409)

Description

一般描述

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Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

应用

甘氨酸是一种非必需氨基酸。 它是最简单的氨基酸，在生物学中具有多种作用。 在生物氨基酸中，甘氨酸结构的独特之处在于它不具有不对称中心，因此不是手性的。 它常被用作细胞培养基成分，用于治疗性重组蛋白和单克隆抗体的商业化生物制造。

生化/生理作用

脊髓中的抑制性神经递质，NMDA受体的变构调节器。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• 储存分类代码: 13 - Non Combustible Solids
• WGK: WGK 1
• 个人防护装备: Eyeshields, Gloves, type N95 (US)