Merck
All Photos(2)

G5417

SAFC

甘氨酸

Synonym(s):
氨基乙酸, 甘氨酸
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.25

生物来源

non-animal source

质量水平

测定

≥98.5%

形式

crystalline powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

杂质

endotoxin, heavy metals, trace metals, residual solvents, tested

pH值(酸碱度)

5.9-6.4

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

溶解性

H2O: 100 mg/mL

紫外吸收

λ: 260 nm Amax: ≤0.04
λ: 260 nm Amax: -0.006
λ: 280 nm Amax: ≤0.04
λ: 280 nm Amax: -0.003

适用性

suitable for manufacturing use

application(s)

pharmaceutical (small molecule)

异质活性

cytotoxicity, tested

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

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This Item
G8898G889850058
Glycine

SAFC

G5417

甘氨酸

Glycine suitable for electrophoresis, ≥99%

Sigma-Aldrich

G8898

甘氨酸

Glycine suitable for electrophoresis, ≥99%

Sigma-Aldrich

G8898

甘氨酸

Glycine tested according to Ph. Eur.

Sigma-Aldrich

50058

甘氨酸

assay

≥98.5%

assay

≥99%

assay

≥99%

assay

100.0%

form

crystalline powder

form

powder

form

powder

form

crystalline

technique(s)

cell culture | mammalian: suitable

technique(s)

electrophoresis: suitable, western blot: suitable

technique(s)

electrophoresis: suitable, western blot: suitable

technique(s)

-

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

impurities

≤0.01% Insoluble matter

impurities

≤0.01% Insoluble matter

impurities

-

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

solubility

H2O: 100 mg/mL

solubility

H2O: 200 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 200 mg/mL, clear, colorless to faintly yellow

solubility

-

一般描述

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Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

应用

甘氨酸是一种非必需氨基酸。 它是最简单的氨基酸,在生物学中具有多种作用。 在生物氨基酸中,甘氨酸结构的独特之处在于它不具有不对称中心,因此不是手性的。 它常被用作细胞培养基成分,用于治疗性重组蛋白和单克隆抗体的商业化生物制造。

生化/生理作用

脊髓中的抑制性神经递质,NMDA受体的变构调节器。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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