Merck
All Photos(3)

G8898

Sigma-Aldrich

甘氨酸

suitable for electrophoresis, ≥99%

Synonym(s):
氨基乙酸, 甘氨酸
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:

质量水平

测定

≥99%

形式

powder

technique(s)

electrophoresis: suitable
western blot: suitable

杂质

≤0.01% Insoluble matter

颜色

white to off-white

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

溶解性

H2O: 200 mg/mL, clear, colorless to faintly yellow

痕量阴离子

chloride (Cl-): ≤70 ppm

痕量阳离子

heavy metals (as Pb): ≤20 ppm

吸光度

≤0.15 at 280 at 1 M

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

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USP

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Sigma-Aldrich

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甘氨酸

assay

≥99%

assay

-

assay

≥99.0% (NT)

assay

≥98.5%

form

powder

form

-

form

crystalline

form

crystals, powder or granules

technique(s)

electrophoresis: suitable, western blot: suitable

technique(s)

-

technique(s)

-

technique(s)

-

impurities

≤0.01% Insoluble matter

impurities

-

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

impurities

H2SO4, passes test (darkened), Hydrolyzable subsances, passes test

color

white to off-white

color

-

color

white

color

-

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

一般描述

甘氨酸是一种pI为6.7的分子,其类似于积层胶的pH。它具有低流动性、疏水性并不与蛋白结合的优点。甘氨酸是用于聚丙烯酰胺凝胶电泳的Tris-甘氨酸和Tris-甘氨酸-SDS(十二烷基硫酸钠)电泳缓冲液中的一种组分。甘氨酸也是用于蛋白质免疫印迹的Towbinz转膜缓冲液的一组组分。

应用

  • 甘氨酸已用于明胶复合支架的制备。
  • 它已用于使用HiTrap G蛋白柱进行蛋白提取的洗脱缓冲液。
  • 它还用于SDS-PAGE(十二烷基硫酸钠聚丙烯酰胺凝胶电泳)及western blotting中的SDS-样品、电泳缓冲液及转膜缓冲液制备。

生化/生理作用

脊髓中的抑制性神经递质,NMDA受体的变构调节器。

分析说明

经过检测,可用于 PAGE 电极缓冲液和蛋白质印迹转移缓冲液。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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