Merck
All Photos(2)

H2625

Sigma-Aldrich

血红蛋白 来源于牛血液

suitable for protease substrate, substrate powder

Synonym(s):
Hb, 牛血红蛋白, 高铁血红蛋白
CAS Number:
MDL编号:
eCl@ss:
42030116
NACRES:
NA.61

生物来源

bovine blood

质量水平

300

形式

substrate powder

分子量

Mr ~64500

technique(s)

activity assay: suitable

溶解性

H2O: soluble 20 mg/mL

适用性

suitable for protease substrate

储存温度

2-8°C

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一般描述

Hemoglobin is the major component of red blood cells and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is a globular protein with α and β chains with every 141 and 146 amino acids respectively. It exists as a tetramer with each monomer having heterocyclic porphyrin ring with iron constituting the heme.
Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.

应用

Hemoglobin from bovine blood has been used as a substrate in cathepsin D activity assay. It has also been used to measure the activity of acid proteases (pepsin-like) in the stomach extract.
α-弹性蛋白的溶解度已被应用于弹性蛋白模拟生物材料的构建。

包装

25, 100 g in glass bottle
1 kg in poly drum

生化/生理作用

氧气转运蛋白。Fe2+/Fe3+平衡是血液氧合的一种生理指标;脱氧血红蛋白通过将亚硝酸还原为NO来补充反馈回路,而NO是一种可增强血液流向缺氧组织流量的血管扩张剂。
Bovine hemoglobin is used in the production of hemoglobin-vesicles (HbV). It has high thermal stability and high oxygen affinity when compared to human hemoglobin. Bovine hemoglobin interacts with synthetic and azo dyes. Polymerized forms of bovine hemoglobin are used to treat autoimmune hemolytic anemia.

注意

由于天然血红蛋白在空气中易于氧化,因此这些制剂主要为高铁血红蛋白。

制备说明

Prepared from washed, lysed and dialyzed erythrocytes.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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Product Information Sheet

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