Merck
All Photos(2)

H3911

SAFC

L-组氨酸

Synonym(s):
(S)-2-氨基-3-(4-咪唑基)丙酸, NSC 137773
Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
Molecular Weight:
155.15
Beilstein:
84088
EC 号:
MDL编号:
eCl@ss:
32160406
NACRES:
NA.26

生物来源

non-animal source

质量水平

检测方案

≥98.5%

形式

crystalline powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

杂质

endotoxin, heavy metals, trace metals, residual solvents, tested

mp

282 °C (dec.) (lit.)

溶解性

H2O: 50 mg/mL

适用性

suitable for manufacturing use

application(s)

pharmaceutical (small molecule)

异质活性

cytotoxicity, tested

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

InChI key

HNDVDQJCIGZPNO-YFKPBYRVSA-N

Gene Information

human ... CA1(759) , CA2(760)

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L-Histidine

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H3911

L-组氨酸

L-Histidine certified reference material, TraceCERT®

Supelco

73767

L-组氨酸

L-Histidine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1108

L-组氨酸

L-Histidine United States Pharmacopeia (USP) Reference Standard

USP

1308505

L-组氨酸

assay

≥98.5%

assay

-

assay

-

assay

-

form

crystalline powder

form

-

form

-

form

-

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

impurities

-

impurities

-

impurities

-

mp

282 °C (dec.) (lit.)

mp

282 °C (dec.) (lit.)

mp

282 °C (dec.) (lit.)

mp

282 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

solubility

-

solubility

-

solubility

-

一般描述

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Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

应用

L-组氨酸是一种必需氨基酸。它用作细胞培养基组分,用于治疗性重组蛋白和单克隆抗体的商业生物制造。

生化/生理作用

组胺的前体,经组氨酸脱羧酶作用可生成组胺。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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