Merck
All Photos(1)

H7125

Sigma-Aldrich

组胺

≥97.0%

Synonym(s):
2-(4-咪唑基)乙胺
Empirical Formula (Hill Notation):
C5H9N3
CAS Number:
Molecular Weight:
111.15
Beilstein:
2012
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.77

质量水平

200

测定

≥97.0%

bp

167 °C/0.8 mmHg (lit.)

mp

83-84 °C (lit.)

储存温度

−20°C

SMILES string

NCCc1c[nH]cn1

InChI

1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)

InChI key

NTYJJOPFIAHURM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

一般描述

组胺是由下丘脑后部神经元产生的神经递质。大脑中,组胺主要存在于灰质部分。

应用

组胺用于:
  • 刺激调节型细胞分泌
  • 在反应混合物中,活化血液,通过荧光测定法测定凝血酶(因子iia)活性
  • 填充腔室腔侧,研究其对TJ相关屏障的影响以及声带上皮中TJ(紧密连接)标志物的表达

包装

1, 5, 25 g in glass bottle

生化/生理作用

内源性 H1 和 H2 组胺受体激动剂;H1 的活化可以使 Ca2+ 移动;H2 的活化可促进神经元中腺苷酸环化酶的活性;活化一氧化氮合成酶;有效的血管舒张剂。
组胺参与先天免疫应答和获得性免疫应答,介导过敏和炎症。有助于肠道肌肉收缩。在过敏性休克过程中,组胺引起​​支气管收缩。组胺还参与分泌胃酸、控制上皮和内皮屏障。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service