Merck

M5308

Sigma-Aldrich

L-甲硫氨酸

from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

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别名:
L-2-氨基-4-(甲硫基)丁酸, (S)-2-氨基-4-(甲巯基)丁酸
线性分子式:
CH3SCH2CH2CH(NH2)CO2H
CAS号:
分子量:
149.21
Beilstein:
1722294
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26

生物来源

non-animal source

质量水平

Agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

产品线

BioXtra

检测方案

99.0-101.0%

形式

powder

质量

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

杂质

endotoxin, tested

颜色

white

mp

284 °C (dec.) (lit.)

溶解性

H2O: 25 mg/mL

application(s)

peptide synthesis
pharmaceutical (small molecule)

SMILES string

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

Gene Information

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此商品
64319M9625PHL82585
L-Methionine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Sigma-Aldrich

M5308

L-甲硫氨酸

Premium Grade
L-Methionine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

64319

L-甲硫氨酸

Premium Grade
L-Methionine reagent grade, ≥98% (HPLC)

Sigma-Aldrich

M9625

L-甲硫氨酸

Essential Grade
L-Methionine phyproof® Reference Substance

PHL82585

L-甲硫氨酸

-
assay

99.0-101.0%

assay

≥99.5% (NT)

assay

≥98% (HPLC)

assay

≥95.0% (HPLC)

form

powder

form

powder or crystals

form

powder

form

crystals

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

-

impurities

endotoxin, tested

impurities

insoluble matter, passes filter test, ≤0.5% foreign amino acids

impurities

-

impurities

-

color

white

color

white

color

white

color

-

应用

L-蛋氨酸已被用作各种癌症细胞培养中培养基的一个组分,以研究其对细胞周期的影响。它还被用作DMEM培养基的组成部分,用于培养鳟鱼白色肌肉中的卫星细胞。

生化/生理作用

蛋氨酸是一种必需氨基酸,它是转甲基化和转硫的前体。在蛋白质中,其生物活性形式为 L-蛋氨酸。蛋氨酸的腺苷化作用形成S-腺苷-L-蛋氨酸(SAM),SAM是许多物质的甲基供体。L-蛋氨酸的代谢产物谷胱甘肽已知可调节免疫反应并具有抗病毒作用。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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货号
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包装规格/数量

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Suppression by L-Methionine of Cell Cycle Progression in LNCaP and MCF-7 Cells but not Benign Cells
Maximo A
Anticancer Research (2010)
L-methionine as immune supportive supplement: a clinical evaluation.
Van Brummelen
Amino Acids, 33(1) (2007)
miR-210 expression is associated with methionine-induced
differentiation of trout satellite cells
Mary Latimer
The Journal of Experimental Biology (2017)
Bio-Methionine Production from Glucose - Cost Analysis - Methionine E31A (2016)
Chien-Kuang Cornelia Ding et al.
Nature metabolism, 2(3), 270-277 (2020-05-29)
Critical to the bacterial stringent response is the rapid relocation of resources from proliferation toward stress survival through the respective accumulation and degradation of (p)ppGpp by RelA and SpoT homologues. While mammalian genomes encode MESH1, a homologue of the bacterial

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