Merck
All Photos(1)

P5780

Sigma-Aldrich

腐胺 二盐酸盐

powder, BioReagent, suitable for cell culture

Synonym(s):
1,4-丁二胺 二盐酸盐, 1,4-二氨基丁烷 二盐酸盐, 四亚甲基二胺 二盐酸盐
Linear Formula:
NH2(CH2)4NH2 · 2HCl
CAS Number:
Molecular Weight:
161.07
Beilstein:
3906680
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.75

生物来源

microbial
synthetic

质量水平

200

产品线

BioReagent

测定

≥97% (TLC)

形式

powder

technique(s)

cell culture | mammalian: suitable

mp

280 °C (dec.) (lit.)

溶解性

H2O: 100 mg/mL

SMILES string

Cl[H].Cl[H].NCCCCN

InChI

1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H

InChI key

XXWCODXIQWIHQN-UHFFFAOYSA-N

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一般描述

腐胺是死亡组织脂肪酸代谢的最终产物。是具有刺激性气味的挥发性二胺。在鸟氨酸脱羧酶存在的情况下,由鸟氨酸脱羧而成。 分子对接研究揭示,在嗅上皮中存在称为痕量胺相关受体(TAAR6和TAAR8)的人类受体,腐胺可以与之结合。

应用

腐胺二盐酸盐作为F-12 + GlutaMax培养基成分,用于小鼠神经节培养视网膜神经节细胞培养和 HCT116 结肠癌细胞中鸟胺酸脱羧酶(ODC)测定。

生化/生理作用

结合到 NMDA 受体的聚胺调控位点并增强 NMDA 感应电流;亚精胺的前体。
腐胺被认为是植物处于胁迫的标志物。补充外源腐胺有助于小麦克服干旱胁迫。腐胺对动物细胞增殖至关重要,同时还可调节处于冷胁迫拟南芥属植物的脱落酸(ABA)水平。可以作为捕食者引诱剂。

象形图

CorrosionSkull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

储存分类代码

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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