Merck
  • R5143
All Photos(1)

R5143

Sigma-Aldrich

芸香素 水合物

≥94% (HPLC), powder

Synonym(s):
Quercetin-3-rutinoside 水合物, Vitamin P 水合物
Empirical Formula (Hill Notation):
C27H30O16 · xH2O
CAS Number:
Molecular Weight:
610.52 (anhydrous basis)
Beilstein:
75455
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.25

质量水平

测定

≥94% (HPLC)

形式

powder

颜色

yellow to green

mp

195 °C (dec.) (lit.)

溶解性

pyridine: 50 mg/mL
DMSO: soluble
aqueous base: soluble

SMILES string

[H]O[H].O[C@H]1[C@H](OC[C@H]([C@H]2O)O[C@@H](OC(C3=O)=C(C4=CC=C(O)C(O)=C4)OC5=C3C(O)=CC(O)=C5)[C@H](O)[C@H]2O)O[C@H]([C@@H]([C@H]1O)O)C

InChI

1S/C27H30O16.H2O/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9;/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3;1H2/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-;/m0./s1

InChI key

PGHSKTKIQIBATG-ZAAWVBGYSA-N

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This Item
78095003005901606503
Rutin hydrate ≥94% (HPLC), powder

Sigma-Aldrich

R5143

芸香素 水合物

Rutin trihydrate analytical standard

Supelco

78095

芦丁 三水合物

Rutin trihydrate primary reference standard

00300590

芦丁 三水合物

Rutin trihydrate United States Pharmacopeia (USP) Reference Standard

USP

1606503

芦丁 三水合物

assay

≥94% (HPLC)

assay

≥94.0% (HPLC)

assay

-

assay

-

form

powder

form

-

form

-

form

-

color

yellow to green

color

-

color

-

color

-

solubility

pyridine: 50 mg/mL, DMSO: soluble, aqueous base: soluble

solubility

-

solubility

-

solubility

-

Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

-

mp

195 °C (dec.) (lit.)

mp

-

mp

-

mp

-

一般描述

Rutin hydrate has radioprotective and antiplatelet activity. Rutin reduces hepatic and blood cholesterol levels.

应用

Rutin hydrate has been used:
  • as an inhibitory compound against Skeletonema costatum
  • to analyze the phenolic component and antioxidant activity of nettle
  • to assess the flavonoid content in Propolis

生化/生理作用

A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodiumethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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