Merck
All Photos(1)

S0266

Sigma-Aldrich

精脒

BioReagent, for molecular biology, suitable for cell culture, ≥98%

Synonym(s):
1,8-二氨基-4-氮杂辛烷, N-(3-氨基丙基)-1,4-丁烷
Linear Formula:
NH2(CH2)3NH(CH2)4NH2
CAS Number:
Molecular Weight:
145.25
Beilstein:
1698591
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.52

等级

for molecular biology

质量水平

200

产品线

BioReagent

测定

≥98%

形式

solid or liquid

technique(s)

cell culture | mammalian: suitable

折射率

n20/D 1.479 (lit.)

密度

0.925 g/mL at 25 °C (lit.)

异质活性

DNase, RNase, and protease, none detected

储存温度

room temp

SMILES string

NCCCCNCCCN

InChI

1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2

InChI key

ATHGHQPFGPMSJY-UHFFFAOYSA-N

Gene Information

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一般描述

亚精胺属于天然多胺,存在于叶绿体、细菌或真核细胞中。

应用

亚精胺可用于制备金珠并用作核分离缓冲液(NIB)成分。
精胺适合用于分子生物缓冲液和> 100 bp DNA沉淀。它被用来在植物和哺乳动物细胞中,通过粒子轰击技术,传递DNA。

生化/生理作用

亚精胺有助于维持基因表达的正常活性。此多胺在中间代谢中起关键作用。也可用作E1A相关蛋白p300(EP300)乙酰转移酶活性的抑制剂。亚精胺参与细胞生长。
抑制神经元型一氧化氮合成酶(nNOS)。结合和沉淀DNA,可用于DNA结合蛋白纯化。激活T4聚核苷酸激酶活性。

注意

如果需要无菌溶液,则应采用无菌过滤而非高压灭菌。时间一长,亚精胺将发生脱氨基作用;溶液应采用冷冻保存。通常需要配制新溶液。

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Corr. 1B

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

闪点(F)

233.6 °F - closed cup

闪点(C)

112 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificate of Analysis

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Certificate of Origin

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