SAB1409429

Anti-PDHA1 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

• Synonym(s): PDHA, PDHCE1A, PHE1A
• NACRES: NA.41

Properties

• 生物来源: mouse
• 质量水平: 100
• 偶联物: unconjugated
• 抗体形式: purified immunoglobulin
• antibody product type: primary antibodies
• 克隆: polyclonal
• 形式: buffered aqueous solution
• 分子量: antigen 93.3 kDa
• species reactivity: human
• technique(s): western blot: 1 μg/mL
• NCBI登记号: NM_000284.1
• UniProt登记号: P08559
• 运输: dry ice
• 储存温度: −20°C
• Gene Information: human ... PDHA1(5160)

Description

一般描述

The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM

免疫原

PDHA1 (NP_000275.1, 1 a.a. ~ 390 a.a) full-length human protein.

Sequence
MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS

包装

50 μg

外形

Solution in phosphate buffered saline, pH 7.4

Safety Information

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 3
• 闪点(F): Not applicable
• 闪点(C): Not applicable