Merck
  • T4382
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T4382

Sigma-Aldrich

脱铁转铁蛋白 人

powder, ≥98% (agarose gel electrophoresis)

Synonym(s):
人转铁蛋白, 铁传递蛋白
CAS Number:
EC 号:
MDL编号:

生物来源

human

质量水平

测定

≥98% (agarose gel electrophoresis)

形式

powder

分子量

76-81 kDa

铁含量

≤0.005%

technique(s)

cell culture | mammalian: suitable

杂质

HIV and HBsAg, source material tested negative

溶解性

H2O: 50 mg/mL

UniProt登记号

运输

wet ice

储存温度

−20°C

Gene Information

human ... TF(7018)

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apo-Transferrin human powder, ≥98% (agarose gel electrophoresis)

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T4382

脱铁转铁蛋白 人

holo-Transferrin human powder, BioReagent, suitable for cell culture, ≥97%

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T0665

全转铁蛋白 人

apo-Transferrin human powder, BioReagent, suitable for cell culture, ≥98% (agarose gel electrophoresis)

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T1147

脱铁转铁蛋白 人

biological source

human

biological source

bovine

biological source

human plasma

biological source

human plasma

assay

≥98% (agarose gel electrophoresis)

assay

≥98%

assay

≥97%

assay

≥98% (agarose gel electrophoresis)

form

powder

form

powder

form

powder

form

powder

mol wt

76-81 kDa

mol wt

-

mol wt

-

mol wt

76-81 kDa

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

impurities

HIV and HBsAg, source material tested negative

impurities

-

impurities

HIV and HBsAg, none detected, endotoxin, tested

impurities

HIV and HBsAg, source material tested negative, ≤0.005% iron

一般描述

人类Apo-转铁蛋白是一种具有同源羧基和氨基结构域的糖蛋白。两种结构域都与一分子的铁结合。在氨基结构域中只有30%的转铁蛋白是铁饱和的。人体中的Apo-转铁蛋白由定位于人类染色体3q22.1的TF基因所编码。

应用

人类Apo-转铁蛋白已被用于:
  • 通过快速高效液相色谱(FPLC)测定铋与白蛋白和转铁蛋白的竞争性结合
  • 通过电化学法研究钛-转铁蛋白络合物
  • 制备转铁蛋白溶液并与钌配合物形成偶联物以用于细胞活力研究

生化/生理作用

Apo-转铁蛋白对少突胶质细胞的存活和分化是必需的。
Apo-转铁蛋白是一种铁转运蛋白。血浆中转铁蛋白的浓度约为35μM。转铁蛋白也还用于转运治疗性、诊断性和毒性离子如Ga3+、Ru3+和Al3+TF基因的多态性在帕金森′病中具有病理学意义。

其他说明

非血红素铁转运蛋白。

联系

与T 2252相似

储存分类代码

11 - Combustible Solids

WGK

WGK 3

Certificate of Analysis

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Certificate of Origin

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