Merck
所有图片(1)

文件

U0881

Sigma-Aldrich

尿酸

BioXtra, ≥99% (HPLC)

所有图片(1)
别名:
2,6,8-三羟基嘌呤
Empirical Formula (Hill Notation):
C5H4N4O3
CAS号:
69-93-2
分子量:
168.11
Beilstein:
156158
EC 号:
200-720-7
MDL编号:
MFCD00005712
PubChem化学物质编号:
24900620
NACRES:
NA.55

生物来源

animal (seabird feces (guano))

产品线

BioXtra

检测方案

≥99% (HPLC)

形式

powder

杂质

≤0.005% Phosphorus (P)

灼烧残渣

≤0.1%

mp

>300 °C (lit.)

溶解性

1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

痕量阳离子

Al: ≤0.005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.05%
Mg: ≤0.001%
NH4+: ≤0.05%
Na: ≤0.1%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)

InChI key

LEHOTFFKMJEONL-UHFFFAOYSA-N

正在寻找类似产品? Visit 产品对比指南

相关类别

比较类似商品

查看完整比较结果

Show Differences

1 of 4

此商品
U2625NIST913BU6753
Uric acid BioXtra, ≥99% (HPLC)

Sigma-Aldrich

U0881

尿酸

Uric acid ≥99%, crystalline

Sigma-Aldrich

U2625

尿酸

Uric acid NIST® SRM® 913b

NIST913B

尿酸

Ursolic acid ≥90%

Sigma-Aldrich

U6753

熊果酸

assay

≥99% (HPLC)

assay

≥99%

assay

-

assay

≥90%

form

powder

form

crystalline

form

crystalline (solid)

form

-

impurities

≤0.005% Phosphorus (P)

impurities

-

impurities

-

impurities

-

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

292 °C (dec.) (lit.)

solubility

1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

solubility

-

solubility

-

solubility

-

一般描述

尿酸是人类嘌呤降解的最终产物。它是由黄嘌呤氧化酶对黄嘌呤的作用形成。尿酸水平升高在临床上表现为痛风。在除人类以外的物种中，尿酸可进一步代谢。在除灵长类动物以外的哺乳动物中，尿酸可转化为尿囊素。在硬骨鱼中，尿囊素可进一步转化为尿囊酸盐，然后水解成尿素和乙醛酸。尿酸还可用于嘌呤的生物合成。它已被研究用作过氧亚硝基等生物自由基的清除剂。已有相关文献发表了关于尿酸的高效液相色谱（HPLC）和气相色谱-质谱（GC-MS）法。尿酸可促进血管平滑肌细胞中单核细胞趋化蛋白-1（MCP-1）的表达。

应用

尿酸已用于：
  • 制备尿酸钠（MSU）结晶，以研究其对核定位富含亮氨酸重复序列1（NLRP1）基因表达的影响
  • 还原剂，以测试其对正铁肌红蛋白形成的保护能力
  • 制备MSU，以研究其作为Clec12a特异性配体的用途。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

在网站页面上，产品编号会附带包装尺寸/数量一起显示（例如：T1503-25G）。请确保 在“产品编号”字段中仅输入产品编号 (示例 T1503).

示例

T1503
货号
-
25G
包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

请输入1.000309185)

遇到问题？欢迎随时联系我们技术服务 寻求帮助

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich 产品

  • 如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。

  • 如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。

  • 如果您查询到的批号含有填充代码（例如 STBB0728K9），请输入去除填充代码K9的批号：STBB0728。

未找到您寻找的产品？

部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。

索取COA

其他客户在看

Slide 1 of 7

1 of 7

Sigma-Aldrich

Sigma-Aldrich

U7128

尿酸酶 来源于球形节杆菌

Oxonic acid potassium salt 97%

Sigma-Aldrich

156124

氧尼酸 钾盐

Xanthine ≥99.5% (HPLC), purified by recrystallization

Sigma-Aldrich

X0626

黄嘌呤

Allantoin ≥98.0% (N)

Sigma-Aldrich

05670

尿囊素

Hypoxanthine ≥99.0%

Sigma-Aldrich

H9377

次黄嘌呤

Xanthine ≥99%

Sigma-Aldrich

X7375

黄嘌呤

Creatinine hydrochloride ≥97%

Sigma-Aldrich

C6257

肌酐 盐酸盐

Waleed Al Abdulmonem et al.
Protein and peptide letters, 28(3), 282-289 (2020-09-23)
Myoglobin is an oxygen binding protein and its dysfunction has been associated with the pathology of several human disorders. This study was undertaken to investigation the role of hydrogen peroxide (H2O2) in the formation of met-myoglobin and the protective potential
H Ulrich Hink et al.
Arteriosclerosis, thrombosis, and vascular biology, 22(9), 1402-1408 (2002-09-17)
The cytosolic form of Cu/Zn-containing superoxide dismutase (SOD1) has peroxidase activity, with H2O2 used as a substrate to oxidize other molecules. We examined peroxidase properties of the extracellular form of SOD (SOD3), a major isoform of SOD in the vessel
John Kanellis et al.
Hypertension (Dallas, Tex. : 1979), 41(6), 1287-1293 (2003-05-14)
Previous studies have reported that uric acid stimulates vascular smooth muscle cell (VSMC) proliferation in vitro. We hypothesized that uric acid may also have direct proinflammatory effects on VSMCs. Crystal- and endotoxin-free uric acid was found to increase VSMC monocyte
R B Kean et al.
Journal of immunology (Baltimore, Md. : 1950), 165(11), 6511-6518 (2000-11-22)
Uric acid (UA), a product of purine metabolism, is a known scavenger of peroxynitrite (ONOO(-)), which has been implicated in the pathogenesis of multiple sclerosis and experimental allergic encephalomyelitis (EAE). To determine whether the known therapeutic action of UA in
Konstantin Neumann et al.
Immunity, 40(3), 389-399 (2014-03-19)
Recognition of cell death by the innate immune system triggers inflammatory responses. However, how these reactions are regulated is not well understood. Here, we identify the inhibitory C-type lectin receptor Clec12a as a specific receptor for dead cells. Both human
查看所有相关文献

商品

Uric Acid in Cell Culture

Uric acid is not a direct additive to any of the classical cell culture media. However, it is present in animal sera. Consequently, uric acid is typically present in complete serum-supplemented classical cell culture systems.

相关内容

Uric Acid in Cell Culture

Uric acid is not a direct additive to any of the classical cell culture media. However, it is present in animal sera. Consequently, uric acid is typically present in complete serum-supplemented classical cell culture systems.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门