Merck

U2625

Sigma-Aldrich

尿酸

≥99%, crystalline

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别名:
2,6,8-三羟基嘌呤
Empirical Formula (Hill Notation):
C5H4N4O3
CAS号:
分子量:
168.11
Beilstein:
156158
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.55

检测方案

≥99%

形式

crystalline

mp

>300 °C (lit.)

SMILES string

O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)

InChI key

LEHOTFFKMJEONL-UHFFFAOYSA-N

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此商品
U0881490997U2875
Uric acid ≥99%, crystalline

Sigma-Aldrich

U2625

尿酸

-
Uric acid BioXtra, ≥99% (HPLC)

Sigma-Aldrich

U0881

尿酸

Premium Grade
Uric acid-1,3-15N2 98 atom % 15N

Sigma-Aldrich

490997

尿酸-1,3-15N2

-
Uric acid sodium salt

Sigma-Aldrich

U2875

尿酸 钠盐

-
form

crystalline

form

powder

form

solid

form

powder

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

-

Quality Level

100, 200

Quality Level

200

Quality Level

200

Quality Level

200

应用

尿酸可以用于:
  • 诱导小鼠高尿酸血症
  • 作为刺激体外人消化模型的消化液组分
  • 选择性检测基于汗液的糖尿病监测葡萄糖感应器

生化/生理作用

尿酸是一种腺嘌呤和鸟嘌呤产生的不溶性分解代谢物。尿酸积累导致痛风,高尿酸血症,关节炎和肾功能衰竭。尿酸水平升高导致高血压与心血管疾病发病。低尿酸水平和帕金森症和多发性硬化有关,可能引发保护性功能。慢性阻塞性肺(COPD)病人高水平尿酸可用作潜在诊疗标记物。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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T1503
货号
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25G
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Sigma-Aldrich

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盐酸多巴胺 盐酸盐

Uric acid in plants and microorganisms: Biological applications and genetics-A review
Hafez RM, et al.
Journal of Advanced Research, 8(5), 475-486 (2017)
Reduction of Serum Uric Acid Associated with Attenuation of Renal Injury, Inflammation and Macrophages M1/M2 Ratio in Hyperuricemic Mice Model
HARYONO A, et al.
Kobe J. Med. Sci., 64(3), E107-E114 (2018)
Serum uric acid: a risk factor and a target for treatment?
Feig DI, et al.
Journal of the American Society of Nephrology, 17(4), S69-S73 (2006)
Serum uric acid as a predictor of mortality and future exacerbations of COPD
Bartziokas K, et al.
The European Respiratory Journal, 43(1), 43-53 (2014)
Uric acid, hyperuricemia and vascular diseases
Jin M, et al.
Frontiers in Bioscience, 17, 656-656 (2012)

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Uric Acid in Cell Culture

Uric acid is not a direct additive to any of the classical cell culture media. However, it is present in animal sera. Consequently, uric acid is typically present in complete serum-supplemented classical cell culture systems.

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Uric Acid in Cell Culture

Uric acid is not a direct additive to any of the classical cell culture media. However, it is present in animal sera. Consequently, uric acid is typically present in complete serum-supplemented classical cell culture systems.

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