Merck
所有图片(3)

U6381

Sigma-Aldrich

尿核甙

BioUltra, ≥99%

别名:
尿嘧啶-1-β-D-呋喃核糖苷, 尿苷
Empirical Formula (Hill Notation):
C9H12N2O6
CAS号:
分子量:
244.20
Beilstein:
754902
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.26

产品线

BioUltra

质量水平

200

测定

≥99%

杂质

≤0.016% Phosphorus (P)
≤0.1% Insoluble matter

灼烧残渣

≤0.2%

mp

163-167 °C (lit.)

溶解性

H2O: 0.1 M, clear, colorless

痕量阳离子

Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.003%
K: ≤0.005%
Mg: ≤0.003%
NH4+: ≤0.15%
Na: ≤0.02%
Pb: ≤0.005%
Zn: ≤0.0005%

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O

InChI

1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

InChI key

DRTQHJPVMGBUCF-XVFCMESISA-N

Gene Information

mouse ... Uck1(22245)

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一般描述

尿苷是一种嘧啶核苷,对 RNA 和膜的合成至关重要。它通过形成嘧啶核苷酸-脂质缀合物来帮助正常细胞功能和生长。

应用

尿苷已被用于研究原生动物寄生虫的核苷水解酶和哺乳动物尿苷磷酸化酶在酿酒酵母的URH1(尿苷水解酶)上的功能互补。
它已用于检查长期应用尿苷对小鼠肝脏代谢的影响。

包装

5, 25 g in poly bottle

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

请输入批号搜索分析证书(COA)。

原产地证书 (CofO)

请输入批号搜索原产地证书(COO)。

Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase.
Mitterbauer R, et al.
Applied and Environmental Microbiology, 68, 1336-1343 (2002)
Purinergic and Pyrimidinergic Signalling: Molecular, Nervous and Urogenitary System Function
Handbook of Experimental Pharmacology (2013)
Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice.
Urasaki Y, et al.
PLoS ONE, 11, e0146994-e0146994 (2016)
Qi Qiu et al.
Nature methods, 17(10), 991-1001 (2020-09-02)
Single-cell RNA sequencing offers snapshots of whole transcriptomes but obscures the temporal RNA dynamics. Here we present single-cell metabolically labeled new RNA tagging sequencing (scNT-seq), a method for massively parallel analysis of newly transcribed and pre-existing mRNAs from the same
Juma A M Ali et al.
Molecular pharmacology, 83(2), 439-453 (2012-11-29)
African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host. However, uptake of pyrimidines in bloodstream form trypanosomes has not been investigated, making it difficult to judge the relative importance of salvage and synthesis

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