Merck
所有图片(2)

V1130

Sigma-Aldrich

万古霉素 盐酸盐 来源于东方链霉菌

BioReagent, suitable for plant cell culture

Empirical Formula (Hill Notation):
C66H75Cl2N9O24 · HCl
CAS号:
分子量:
1485.71
Beilstein:
3704657
NACRES:
NA.72

质量水平

200

生物来源

Streptomyces orientalis

产品线

BioReagent

测定

≥900 μg/mg (as vancomycin base)

形式

powder

储存条件

(Keep container tightly closed in a dry and well-ventilated place.)

technique(s)

cell culture | plant: suitable

颜色

off-white to brown

溶解性

H2O: 50 mg/mL, clear, colorless to dark yellow (and Very Faint Orange to Faint Orange)

抗生素抗菌谱

Gram-positive bacteria

application(s)

agriculture

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES string

Cl[H].CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]2C[C@](C)(N)[C@@H](O)[C@@H](C)O2.CN[C@H](CC(C)C)C(=O)NC3[C@H](O)c4ccc(Oc5cc6Oc7ccc(cc7Cl)[C@@H](O)[C@H]8NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC3=O)c(c5)c6)c9ccc(O)c(c9)-c%10c(O)cc(O)cc%10[C@@H](NC8=O)C(O)=O)c(Cl)c4

正在寻找类似产品? Visit 产品对比指南

一般描述

Vancomycin is a heptapeptide.
Chemical structure: glycopeptide

应用

Vancomycin hydrochloride from Streptomyces orientalis has been used as:
  • an antibiotic in screening: minimal inhibitory concentrations (MICs) Streptomyces coelicolor
  • in treating Leishmania infected sand flies
  • in combined antibiotic treatment in asthma induced mice

包装

1, 5 g in glass bottle

生化/生理作用

Vancomycin is used for treating methicillin-resistant Staphylococcus aureus (MRSA) infections and shunt-associated Staphylococcal ventriculitis. It may lead to hypersensitivity reactions like anaphylaxis and red man syndrome. Vanomycin is also used to treat thrombocytopenia and induces drug reaction with eosinophilia and systemic symptoms (DRESS) on usage.
糖肽抗生素
作用模式:用于通过抑制NAM/NAG-肽的末端D-丙氨酰-D-丙氨酸部分的插入在肽聚糖生物合成水平阻断细菌细胞壁生物合成。
抗菌谱:革兰氏阳性菌

其他说明

Keep container tightly closed in a dry and well-ventilated place.

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

分析证书

请输入批号搜索分析证书(COA)。

原产地证书 (CofO)

请输入批号搜索原产地证书(COO)。

T Asano et al.
Phytopathology, 89(4), 314-319 (2008-10-24)
ABSTRACT Resting spores of Plasmodiophora brassicae were surface-disinfested by treatment with 2% chloramine-T for 20 min and then with an antibiotic solution (1,000 ppm of colistin sulfate, 1,000 ppm of vancomycin hydrochloride, and 6,000 ppm of cefotaxime sodium) for 1
Red man syndrome
Sivagnanam S and Deleu D
Critical Care, 7(2), 119-119 (2002)
Early-life antibiotics attenuate regulatory T cell generation and increase the severity of murine house dust mite-induced asthma
Adami AJ, et al.
Pediatric Research, 84(3), 426-426 (2018)
Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive Sepsis
Roy S, et al.
Case reports in immunology, 2019, 119-119 (2019)
Optimization of fermentation conditions for production of glycopeptide antibiotic vancomycin by Amycolatopsis orientalis
Padma PN, et al.
Applied Biochemistry and Biotechnology, 102(1-6), 395-405 (2002)

相关内容

Inhibition of Cell Wall Biosynthesis by Antibiotics

Inhibition of Cell Wall Biosynthesis by Antibiotics

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门