Merck
所有图片(5)

V6629

Sigma-Aldrich

维生素 B 12

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

别名:
Cyanocob(III)alamin, 氰钴胺, α-(5,6-Dimethylbenzimidazolyl)cyanocobamide, CN-Cbl
Empirical Formula (Hill Notation):
C63H88CoN14O14P
CAS号:
分子量:
1355.37
Beilstein:
4122889
EC 号:
eCl@ss:
34058004
PubChem化学物质编号:
NACRES:
NA.75

质量水平

200

生物来源

microbial

产品线

BioReagent

测定

≥98%

形式

powder

分子量

Mw 1355.37 g/mol

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

颜色

red to brown

pH值(酸碱度)

6

溶解性

water: soluble 50 mg/mL, dark red

储存温度

2-8°C

SMILES string

C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@

InChI

1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1

InChI key

RMRCNWBMXRMIRW-QJRSUKKJSA-L

正在寻找类似产品? Visit 产品对比指南

一般描述

氰钴胺(B12)是一种水溶性维生素,通常称为钴胺素。乳制品、肉和蛋是这种维生素的主要来源。

应用

维生素B12已用于:
  • 用作Erdschreiber′s培养基组分
  • 用作杜氏改良Eagle′s培养基补充剂,用于从新生和成年大鼠中分离出的心室肌细胞
  • 雄性鹌鹑口服用药,以研究其在减少亚硒酸钠中毒体内负面影响方面的作用。

包装

1, 5 g in glass bottle
100, 250 mg in glass bottle

生化/生理作用

维生素B12代谢为其甲基钴胺素活性形式。恶性贫血患者体内可观测到维生素B12吸收受阻。维生素B12对成红细胞发育至关重要。妊娠会导致维生素B12水平下降。衰老会到维生素B12吸收减少。它可充当脂肪、碳水化合物和蛋白质代谢中的辅酶。它是细胞生长、遗传稳定性和体外存活必需的成分。参与支持一碳代谢。存在于许多经典和无血清配方中。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

请输入批号搜索分析证书(COA)。

原产地证书 (CofO)

请输入批号搜索原产地证书(COO)。

更多文件

Quotes and Ordering

Selenium toxicosis assessment (in vivo and in vitro) and the protective role of vitamin B12 in male quail (Coturnix coturnix)
Gad MA and El-Twab SMA
Environmental Toxicology and Pharmacology, 27(1), 7-16 (2009)
Vitamins for chronic disease prevention in adults: clinical applications
Fletcher RH and Fairfield KM
JAMA : The Journal of the American Medical Association, 287(23), 3127-3129 (2002)
Effect of nutrients on growth and lipid accumulation in the green algae Dunaliella tertiolecta
Chen M, et al.
Bioresource Technology, 102(2), 1649-1655 (2011)
Vitamins, minerals and trace elements
Drugs During Pregnancy and Lactation (2015)
miRNA-204 drives cardiomyocyte proliferation via targeting Jarid2
Liang D, et al.
International Journal of Cardiology, 201, 38-48 (2015)

技术文章

Vitamin B12, Cobalamin, in Cell Culture

Importance and uses of Vitamin B12 in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell cultures

相关内容

Vitamin B12, Cobalamin, in Cell Culture

Importance and uses of Vitamin B12 in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell cultures

Folic Acid and Tetrahydrofolates in Cell Culture

Importance and uses of folic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures. Folic acid and its reduced derivative(s), such as folinic acid, are an essential water soluble vitamins added to virtually all cell culture media.

Folic Acid and Tetrahydrofolates in Cell Culture

Importance and uses of folic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures. Folic acid and its reduced derivative(s), such as folinic acid, are an essential water soluble vitamins added to virtually all cell culture media.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门