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R Shukla et al.
The International journal of neuroscience, 116(12), 1391-1402 (2006-12-06)
Evidence from clinical and experimental studies supports the hypothesis of free radical-mediated damage of dopaminergic neurons in the pathology of Parkin's disease (PD). The present study was undertaken to evaluate the role of nitric oxide and oxidative stress in PD.
Mutsuko Demizu et al.
Gan to kagaku ryoho. Cancer & chemotherapy, 40(7), 897-900 (2013-07-19)
Cetuximab is a monoclonal antibody that binds to the EGFR, and is used in patients with colorectal cancer. The most common toxicities associated with the use of cetuximab are rash and hypomagnesemia. Hypomagnesemia is a major adverse event, but it
Ask the doctors. I recently developed atrial fibrillation, and my doctor said it was because my magnesium level was low. What would cause this to happen?
Thomas Lee et al.
Harvard heart letter : from Harvard Medical School, 23(8), 2-2 (2013-08-07)
Thi Dong Phuong Nguyen et al.
Environmental technology, 35(9-12), 1378-1388 (2014-04-08)
The freshwater microalga Chlorella vulgaris was harvested by autoflocculation resulting from the precipitation of magnesium or calcium compounds induced by a slow increase in pH in the absence of CO2 input. Autoflocculation was tested in two culture media with, respectively
Jamie D Murphy et al.
Middle East journal of anaesthesiology, 22(1), 11-20 (2013-07-10)
The efficacy of perioperative intravenous magnesium administration on postoperative opioid use, opioid-related side effects (e.g., nausea and vomiting) and pain are uncertain, as randomized controlled trials on this topic have reported disparate results. The objective of this systematic review is
Mario Barbagallo et al.
Metabolism: clinical and experimental, 63(4), 502-509 (2014-01-28)
Several alterations of magnesium metabolism have been associated with type 2 diabetes pathophysiology, a condition particularly frequent in older persons. We aimed to evaluate serum total (Mg-tot) and serum ionized magnesium (Mg-ion) in older persons with type 2 diabetes in
Ragnar Rylander
Journal of water and health, 12(1), 34-40 (2014-03-20)
Studies in many countries have demonstrated a relationship between drinking water mineral content and the risk of death in cardiovascular disease (CVD). Particularly strong relationships have been found for magnesium and it has been suggested that magnesium be added to
Christopher A Strulson et al.
Biochemistry, 52(46), 8187-8197 (2013-11-06)
In an effort to relate RNA folding to function under cellular-like conditions, we monitored the self-cleavage reaction of the human hepatitis delta virus-like CPEB3 ribozyme in the background of physiological ionic concentrations and various crowding and cosolute agents. We found
Denise H M Heppe et al.
The American journal of clinical nutrition, 98(1), 224-232 (2013-05-31)
Maternal diet during pregnancy has been suggested to influence bone health in later life. We assessed the association of maternal first-trimester dietary intake during pregnancy with childhood bone mass. In a prospective cohort study in 2819 mothers and their children
Fang-jian Wang et al.
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 12(3), 144-147 (2004-04-03)
To study on the changes of intracellular calcium and magnesium in cirrhosis and its clinical significance. The calcium and magnesium were determined in serum (SCa, SMg), platelets (PCa, PMg), mononuclear cells (MNCCa, MNCMg), polymorphonuclear cells (PMNCa, PMNMg) and erythrocytes (RCa
On call. I have been experiencing strong muscle cramps that curl my fingers into a claw shape, which I can straighten only by using the other hand. How can I prevent this?
William Kormos
Harvard men's health watch, 17(8), 2-2 (2013-07-03)
Andrea M P Romani
Metal ions in life sciences, 13, 49-79 (2014-01-29)
Mammalian cells tightly regulate cellular Mg(2+) content through a variety of transport and buffering mechanisms under the control of various hormones and cellular second messengers. The effect of these hormones and agents results in dynamic changes in the total content
Elena Fridman et al.
Harefuah, 152(3), 158-161 (2013-05-30)
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in premature infants who have needed mechanical ventilation and oxygen therapy. BPD is defined as the presence of persistent respiratory symptoms, the need for supplemental oxygen to treat hypoxemia, and
E P Pasichna et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 85(5), 137-148 (2014-02-01)
It is known that inflammatory cytokines, which level is significantly increased in the pathogenesis of multiple sclerosis (MS), as well as interferon-beta, which is used to treat autoimmune diseases, can inhibit cytochrome P450-dependent processes of detoxification and biotransformation. The uncontrolled
Craig A Bayse et al.
Biochemistry, 53(30), 5034-5041 (2014-07-16)
Understanding the mechanism of prenyltransferases is important to the design of engineered proteins capable of synthesizing derivatives of naturally occurring therapeutic agents. CloQ is a Mg(2+)-independent aromatic prenyltransferase (APTase) that transfers a dimethylallyl group to 4-hydroxyphenylpyruvate in the biosynthetic pathway
Invited reply to "Treatment of pediatric hypomagnesaemia: a fast and safe way" (PBC-13-0655) by Ismail El-Beshlawi.
Uri S Alon et al.
Pediatric blood & cancer, 61(7), 1157-1157 (2013-08-24)
Jochen Halfar et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(49), 19737-19741 (2013-11-20)
Northern Hemisphere sea ice has been declining sharply over the past decades and 2012 exhibited the lowest Arctic summer sea-ice cover in historic times. Whereas ongoing changes are closely monitored through satellite observations, we have only limited data of past
Y Kotake et al.
Journal of neurochemistry, 65(6), 2633-2638 (1995-12-01)
1-Benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ) was detected as a novel endogenous amine in mouse brain and parkinsonian CSF by using the gas chromatography-selected ion-monitoring method. The level of 1BnTIQ was very high in CSF of some parkinsonian patients compared with that of controls
Grace K Dy et al.
CA: a cancer journal for clinicians, 63(4), 249-279 (2013-05-30)
Answer questions and earn CME/CNE Advances in genomics and molecular biology have identified aberrant proteins in cancer cells that are attractive targets for cancer therapy. Because these proteins are overexpressed or dysregulated in cancer cells compared with normal cells, it
Pallavi K Choudhary et al.
RNA (New York, N.Y.), 20(1), 36-45 (2013-11-19)
Mg(2+) has been shown to modulate the function of riboswitches by facilitating the ligand-riboswitch interactions. The btuB riboswitch from Escherichia coli undergoes a conformational change upon binding to its ligand, coenzyme B12 (adenosyl-cobalamine, AdoCbl), and down-regulates the expression of the
Weifu Wang et al.
European urology, 48(3), 418-423 (2005-06-22)
To review and present the proposals or findings for a new approach about how to define and diagnose premature ejaculation (PE). Using Medline to search for international peer reviewed manuscripts published from 1996 to 2004 about the definition and diagnosis
D A Loeffler et al.
Journal of neural transmission. Parkinson's disease and dementia section, 9(1), 45-53 (1995-01-01)
Though depletion of CSF homovanillic acid (HVA) concentration has often been regarded as a direct indicator of dopamine (DA) deficiency in Parkinson's Disease (PD), CSF HVA is normal in mildly affected patients. To explore why, we measured DA and its
Richard E Bryant et al.
The American journal of the medical sciences, 327(2), 73-76 (2004-02-11)
Restriction of zinc and iron available for microbial growth in tissues are well-recognized host defense mechanisms. The present studies were performed to characterize some constituents of human pus that may affect these important host defenses. Zinc, iron, copper, calcium, and
M O Kristensen et al.
Acta neurologica Scandinavica, 87(6), 475-481 (1993-06-01)
The cobalamin status was evaluated in Alzheimer dementia (n = 26), other dementias (n = 24), various gerontopsychiatric disorders (n = 25), and in neuro-psychiatrically healthy controls (n = 20). Supplementing serum cobalamin we measured methylmalonic acid (MMA), a metabolite
[The role of magnesium in neuroprotection and neuroplasticity].
E S Akarachkova et al.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 113(2), 80-83 (2013-05-15)
M A Raskind et al.
Biological psychiatry, 46(6), 756-765 (1999-09-24)
High cerebrospinal fluid (CSF) norepinephrine (NE) concentrations in aging and Alzheimer's disease (AD) could reflect decreased NE clearance from central nervous system (CNS) extracellular fluid or increased release of NE into CNS extracellular fluid. Measuring CSF concentrations of the intraneuronal
Yi Yin et al.
Zhongguo gu shang = China journal of orthopaedics and traumatology, 26(5), 423-428 (2013-08-14)
To investigate the tissue toxicity and degradation of ZK60 magnesium alloy with micro-arc oxidation coatings (MAO-ZK60), in order to discuss the possibility of its potential application for orthopedic implantation. Eighteen Sprague-Dawley rats were randomized equally to three groups of A
The Grignard Reagents.
Seyferth D
Organometallics, 28(6), 1598-1605 (2009)
Urszula Blaszczyk et al.
Roczniki Panstwowego Zakladu Higieny, 64(3), 165-171 (2013-12-12)
Magnesium (Mg2+) plays a key role in many essential cellular processes such as intermediary metabolism, DNA replication and repair, transporting potassium and calcium ions, cell proliferation together with signalling transduction. Dietary sources rich in magnesium are whole and unrefined grains
Grignard reagent formation.
Garst JF and Soriaga MP
Coordination Chemistry Reviews, 248(7-8), 623-652 (2004)
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页码 1 来自 7