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Rock's power to mop up carbon revisited.
Daniel Cressey
Nature, 505(7484), 464-464 (2014-01-24)
M A Lovell et al.
Archives of neurology, 58(3), 392-396 (2001-03-20)
Markers of oxidative stress are increased in cerebrospinal fluid (CSF) of patients with Alzheimer disease (AD), although none of those reported are appropriate diagnostic markers because of the overlap between patients with AD and control subjects. To determine the ratio
Jeroen H F de Baaij et al.
Physiological reviews, 95(1), 1-46 (2014-12-30)
Magnesium (Mg(2+)) is an essential ion to the human body, playing an instrumental role in supporting and sustaining health and life. As the second most abundant intracellular cation after potassium, it is involved in over 600 enzymatic reactions including energy
M L Selley et al.
Neurobiology of aging, 23(3), 383-388 (2002-04-18)
There is evidence that increased blood concentrations of homocysteine may be a risk factor for Alzheimer's disease. (E)-4-hydroxy-2-nonenal (HNE) is a neurotoxic product of lipid peroxidation that is increased in the ventricular fluid and brains of patients with Alzheimer's disease.
R N Tsepilov et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (2)(2), 12-20 (2013-06-29)
Selection of high-mucoid morphotype of Streptococcus equi subsp. zooepidemicus (Streptococcus zooepidemicus) and study of its morphological, physiological, biochemical and technological characteristics for providing increased secretion of hyaluronic acid (HA). Submerged cultivation was performed in 100 ml glass flasks without baffles
E J Pappert et al.
Neurology, 47(4), 1037-1042 (1996-10-01)
To determine if ventricular cerebrospinal fluid (vCSF) alpha-tocopherol levels in Parkinson's disease (PD) patients can be increased by oral alpha-tocopherol supplementation and whether vCSF levels are linearly related to plasma alpha-tocopherol levels. In spite of its putative neuroprotective properties, alpha-tocopherol
William A Beard et al.
Biochemistry, 53(17), 2768-2780 (2014-04-11)
DNA polymerase (pol) β is a small eukaryotic DNA polymerase composed of two domains. Each domain contributes an enzymatic activity (DNA synthesis and deoxyribose phosphate lyase) during the repair of simple base lesions. These domains are termed the polymerase and
Tahir Rafique et al.
Water environment research : a research publication of the Water Environment Federation, 85(7), 579-586 (2013-08-16)
The role of seawater dilution, along with other water-quality components, has been studied to determine the causes of spatial distribution of high fluoride concentrations in the groundwater of the Diplo sub-district, Thar Desert, Pakistan. Fluoride ion concentration ranges of up
Hangyuan Guo et al.
Herz, 29(3), 299-303 (2004-05-29)
This study sought to clarify the relationship between the degree of intracellular magnesium deficiency and the frequency of anginal attacks in women with variant angina. We evaluated the intracellular and extracellular magnesium status of twelve women with variant angina: group
Nicole T Schirle et al.
Science (New York, N.Y.), 346(6209), 608-613 (2014-11-02)
MicroRNAs (miRNAs) control expression of thousands of genes in plants and animals. miRNAs function by guiding Argonaute proteins to complementary sites in messenger RNAs (mRNAs) targeted for repression. We determined crystal structures of human Argonaute-2 (Ago2) bound to a defined
A Moser et al.
Journal of the neurological sciences, 131(2), 183-189 (1995-08-01)
We could identify the MPTP-like compound and isoquinoline derivative N-methyl-norsalsolinol (2-MDTIQ) in cerebrospinal fluid (CSF) of patients with Parkinson's disease. The presence of 2-MDTIQ negatively correlated with the disease duration. In order to study the relationship between presence of 2-MDTIQ
Nikolai N Sluchanko et al.
Archives of biochemistry and biophysics, 549, 32-39 (2014-04-01)
Members of the 14-3-3 protein family interact with hundreds of different, predominantly phosphorylated, proteins. 14-3-3 dimers are prevalent but exist at the equilibrium with the monomers. Our previous studies using the engineered monomeric 14-3-3ζ (14-3-3ζm) showed that 14-3-3ζ monomer retained
Valerio Leoni et al.
Clinical chemistry and laboratory medicine, 42(2), 186-191 (2004-04-06)
24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed to a lesser extent in the brain than in most other organs. HYPOTHESIS TO BE TESTED:
Jeremy R Keown et al.
The Biochemical journal, 464(3), 413-423 (2014-09-24)
Most plants contain two isoforms of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) activase (Rca), a chloroplast protein that maintains the activity of Rubisco during photosynthesis. The longer (α-) Rca isoform has previously been shown to regulate the activity of Rubisco in response to
Long-Liu Lin et al.
Biochimica et biophysica acta, 1844(9), 1523-1529 (2014-05-02)
γ-Glutamyltranspeptidases (γ-GTs) cleave the γ-glutamyl amide bond of glutathione and transfer the released γ-glutamyl group to water (hydrolysis) or acceptor amino acids (transpeptidation). These ubiquitous enzymes play a key role in the biosynthesis and degradation of glutathione, and in xenobiotic
Yue Hu et al.
Biochemical and biophysical research communications, 436(2), 140-144 (2013-06-04)
Magnesium transporter subtype 1 (MagT1) is a newly discovered and evolutionarily conservative magnesium membrane transporter with channel like properties. Previous reports have demonstrated that MagT1 is important to cellular magnesium homeostasis. In this study, we investigated whether drosophila MagT1 (dMagT1)
Beena Sharma et al.
Pakistan journal of biological sciences : PJBS, 16(18), 965-968 (2014-02-08)
In the present study, accumulation of nutrients (N, P, Ca, Mg, and K) in various plant parts of three different dominant trees i.e., Acacia senegal (As), Acacia tortilis (At) and Eucalyptus camaldulensis (Ec) was estimated. Concentration of nutrients was estimated
Jian-ping Jia et al.
Chinese medical journal, 117(8), 1161-1164 (2004-09-14)
An important aspect of Alzheimer's disease (AD) is loss or impairment of cholinergic neurons. It is controversial whether there is a similar cholinergic impairment and cerebral deficit of acetylcholine (ACh) in the case of vascular dementia (VD). The purpose of
J-M Serot et al.
Journal of neurology, neurosurgery, and psychiatry, 76(11), 1585-1587 (2005-10-18)
Homocysteine may be involved in the pathogenesis of late onset Alzheimer's disease. It is implicated in the metabolism of several important pathways in the brain. Methylmalonic acid (MMA) is related to the metabolism of branched chained amino acids and fatty
Adam Drewnowski et al.
The American journal of clinical nutrition, 99(5 Suppl), 1223S-1228S (2014-03-22)
Nutrient profiling is the technique of rating or classifying foods on the basis of their nutritional value. Foods that supply relatively more nutrients than calories are defined as nutrient dense. Nutrient profile models calculate the content of key nutrients per
Limor Gortzak-Uzan et al.
The Journal of reproductive medicine, 50(11), 817-820 (2006-01-20)
To compare the effect of prolonged maternal intravenous MgSO4 administration on amniotic fluid and serum concentrations of magnesium over time in preterm labor patients. Patients at 24-34 weeks of singleton gestation who presented with contractions (> 8 in 60 minutes)
P A Bakumov et al.
Meditsina truda i promyshlennaia ekologiia, (3)(3), 41-43 (2013-06-22)
The possibility of magnesium deficiency correction was investigated in medical personnel with metabolic syndrome. It was shown that treatment with drugs containing magnesium leads to a decrease the cholesterol level.
Charles L Loprinzi et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(10), 997-1005 (2013-12-04)
Cumulative neurotoxicity is a prominent toxicity of oxaliplatin-based therapy. Intravenous calcium and magnesium have been extensively used to reduce oxaliplatin-induced neurotoxicity. This trial was designed to definitively test whether calcium/magnesium decreases oxaliplatin-related neurotoxicity. In all, 353 patients with colon cancer
V K Kol'tover
Biofizika, 58(2), 257-263 (2013-06-13)
There is a great variety of chemical elements with magnetic and nonmagnetic isotopes in living cells. The question arises as to whether living cells can perceive the difference between magnetic and non-magnetic isotopes of chemical elements. It has been shown
Tatsuya Yoshida et al.
Japanese journal of clinical oncology, 44(4), 346-354 (2014-02-08)
Magnesium supplementation has been reported to have a nephroprotective effect on cisplatin-induced renal dysfunction, but little evidence exists regarding the effect of magnesium preloading before cisplatin administration. We started to include magnesium preloading (8 mEq) in cisplatin-containing treatment regimens in
Chamani P M Marasinghe Wadige et al.
Aquatic toxicology (Amsterdam, Netherlands), 149, 83-93 (2014-03-01)
Lead entering aquatic ecosystems adsorbs to sediments and has the potential to cause adverse effects on the health of benthic organisms. To evaluate the freshwater bivalve Hyridella australis as a bioindicator for sediment toxicity, their exposure-dose and response to lead
E P Pasichna et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 85(5), 137-148 (2014-02-01)
It is known that inflammatory cytokines, which level is significantly increased in the pathogenesis of multiple sclerosis (MS), as well as interferon-beta, which is used to treat autoimmune diseases, can inhibit cytochrome P450-dependent processes of detoxification and biotransformation. The uncontrolled
Lawrence M Resnick et al.
Hypertension (Dallas, Tex. : 1979), 44(3), 322-326 (2004-07-21)
Preeclampsia is a pregnancy disorder of unknown origin, characterized by vasospasm, elevated blood pressure, and increased neuromuscular irritability, features common to syndromes of magnesium deficiency. Evidence of serum and ionized magnesium metabolism disturbances have been observed in women with preeclampsia.
Elena Fridman et al.
Harefuah, 152(3), 158-161 (2013-05-30)
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in premature infants who have needed mechanical ventilation and oxygen therapy. BPD is defined as the presence of persistent respiratory symptoms, the need for supplemental oxygen to treat hypoxemia, and
F H Nielsen et al.
European journal of clinical nutrition, 58(5), 703-710 (2004-04-30)
To determine whether moderately high or low intakes of zinc adversely affect the copper status of postmenopausal women to result in unfavorable changes in calcium and magnesium metabolism and other indicators of bone turnover. After a 10-day equilibration period in
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