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R N Tsepilov et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (2)(2), 12-20 (2013-06-29)
Selection of high-mucoid morphotype of Streptococcus equi subsp. zooepidemicus (Streptococcus zooepidemicus) and study of its morphological, physiological, biochemical and technological characteristics for providing increased secretion of hyaluronic acid (HA). Submerged cultivation was performed in 100 ml glass flasks without baffles
William A Beard et al.
Biochemistry, 53(17), 2768-2780 (2014-04-11)
DNA polymerase (pol) β is a small eukaryotic DNA polymerase composed of two domains. Each domain contributes an enzymatic activity (DNA synthesis and deoxyribose phosphate lyase) during the repair of simple base lesions. These domains are termed the polymerase and
M A Lovell et al.
Archives of neurology, 58(3), 392-396 (2001-03-20)
Markers of oxidative stress are increased in cerebrospinal fluid (CSF) of patients with Alzheimer disease (AD), although none of those reported are appropriate diagnostic markers because of the overlap between patients with AD and control subjects. To determine the ratio
Pishan Chang et al.
The Journal of pharmacology and experimental therapeutics, 352(1), 43-52 (2014-10-19)
The medium chain triglyceride (MCT) ketogenic diet is a major treatment of drug-resistant epilepsy but is problematic, particularly in adults, because of poor tolerability. Branched derivatives of octanoic acid (OA), a medium chain fat provided in the diet have been
Małgorzata Kiełczykowska et al.
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 58(2), 281-284 (2004-08-25)
Lithium is used in medicine. However, its administration can have negative side effects, disturb the water-electrolyte equilibrium and affect the level of essential elements. For these reasons the influence of oral lithium intoxication at the dose of 150 mg Li
Ramanagouda Ramanagoudr-Bhojappa et al.
Biochemistry, 53(48), 7659-7669 (2014-11-14)
Pif1 is a helicase involved in the maintenance of nuclear and mitochondrial genomes in eukaryotes. Here we report a new activity of Saccharomyces cerevisiae Pif1, annealing of complementary DNA strands. We identified preferred substrates for annealing as those that generate
Anirudha Dutta et al.
The FEBS journal, 281(23), 5309-5324 (2014-09-30)
Mg(2+) -dependent, Li(+) -sensitive phosphatases are a widely distributed family of enzymes with significant importance throughout the biological kingdom. Inositol monophosphatase (IMPase) is an important target of Li(+) -based therapeutic agents in manic depressive disorders. However, despite decades of intense
H S Na et al.
Anaesthesia, 69(12), 1314-1321 (2014-08-19)
We investigated the effects of magnesium sulphate on blood coagulation profiles using rotational thromboelastometry in patients undergoing laparoscopic colorectal cancer surgery. Patients were randomly allocated to the magnesium group (n = 22) or control group (n = 22). The magnesium
Marta Guasch-Ferré et al.
The Journal of nutrition, 144(1), 55-60 (2013-11-22)
The relation between dietary magnesium intake and cardiovascular disease (CVD) or mortality was evaluated in several prospective studies, but few of them have assessed the risk of all-cause mortality, which has never been evaluated in Mediterranean adults at high cardiovascular
Ask the doctors. I recently developed atrial fibrillation, and my doctor said it was because my magnesium level was low. What would cause this to happen?
Thomas Lee et al.
Harvard heart letter : from Harvard Medical School, 23(8), 2-2 (2013-08-07)
Tatsuya Yoshida et al.
Japanese journal of clinical oncology, 44(4), 346-354 (2014-02-08)
Magnesium supplementation has been reported to have a nephroprotective effect on cisplatin-induced renal dysfunction, but little evidence exists regarding the effect of magnesium preloading before cisplatin administration. We started to include magnesium preloading (8 mEq) in cisplatin-containing treatment regimens in
P A Bakumov et al.
Meditsina truda i promyshlennaia ekologiia, (3)(3), 41-43 (2013-06-22)
The possibility of magnesium deficiency correction was investigated in medical personnel with metabolic syndrome. It was shown that treatment with drugs containing magnesium leads to a decrease the cholesterol level.
Na Yu et al.
Archives of biochemistry and biophysics, 564, 74-82 (2014-09-30)
Na(+)/Mg(2+) exchanger plays an important role in cardiovascular system, but the molecular mechanisms still largely remain unknown. The Solute Carrier family 41A1 (SLC41A1), a novel Mg(2+) transporter, recently was found to function as Na(+)/Mg(2+) exchanger, which mainly regulates the intracellular
Charles L Loprinzi et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(10), 997-1005 (2013-12-04)
Cumulative neurotoxicity is a prominent toxicity of oxaliplatin-based therapy. Intravenous calcium and magnesium have been extensively used to reduce oxaliplatin-induced neurotoxicity. This trial was designed to definitively test whether calcium/magnesium decreases oxaliplatin-related neurotoxicity. In all, 353 patients with colon cancer
V K Kol'tover
Biofizika, 58(2), 257-263 (2013-06-13)
There is a great variety of chemical elements with magnetic and nonmagnetic isotopes in living cells. The question arises as to whether living cells can perceive the difference between magnetic and non-magnetic isotopes of chemical elements. It has been shown
Jian-ping Jia et al.
Chinese medical journal, 117(8), 1161-1164 (2004-09-14)
An important aspect of Alzheimer's disease (AD) is loss or impairment of cholinergic neurons. It is controversial whether there is a similar cholinergic impairment and cerebral deficit of acetylcholine (ACh) in the case of vascular dementia (VD). The purpose of
Limor Gortzak-Uzan et al.
The Journal of reproductive medicine, 50(11), 817-820 (2006-01-20)
To compare the effect of prolonged maternal intravenous MgSO4 administration on amniotic fluid and serum concentrations of magnesium over time in preterm labor patients. Patients at 24-34 weeks of singleton gestation who presented with contractions (> 8 in 60 minutes)
M L Selley et al.
Neurobiology of aging, 23(3), 383-388 (2002-04-18)
There is evidence that increased blood concentrations of homocysteine may be a risk factor for Alzheimer's disease. (E)-4-hydroxy-2-nonenal (HNE) is a neurotoxic product of lipid peroxidation that is increased in the ventricular fluid and brains of patients with Alzheimer's disease.
Jeroen H F de Baaij et al.
Physiological reviews, 95(1), 1-46 (2014-12-30)
Magnesium (Mg(2+)) is an essential ion to the human body, playing an instrumental role in supporting and sustaining health and life. As the second most abundant intracellular cation after potassium, it is involved in over 600 enzymatic reactions including energy
Treatment of pediatric hypomagnesaemia: a fast and safe way.
Ismail El-Beshlawi
Pediatric blood & cancer, 61(7), 1156-1156 (2013-09-04)
Elena Fridman et al.
Harefuah, 152(3), 158-161 (2013-05-30)
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in premature infants who have needed mechanical ventilation and oxygen therapy. BPD is defined as the presence of persistent respiratory symptoms, the need for supplemental oxygen to treat hypoxemia, and
E P Pasichna et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 85(5), 137-148 (2014-02-01)
It is known that inflammatory cytokines, which level is significantly increased in the pathogenesis of multiple sclerosis (MS), as well as interferon-beta, which is used to treat autoimmune diseases, can inhibit cytochrome P450-dependent processes of detoxification and biotransformation. The uncontrolled
Hangyuan Guo et al.
Herz, 29(3), 299-303 (2004-05-29)
This study sought to clarify the relationship between the degree of intracellular magnesium deficiency and the frequency of anginal attacks in women with variant angina. We evaluated the intracellular and extracellular magnesium status of twelve women with variant angina: group
Rock's power to mop up carbon revisited.
Daniel Cressey
Nature, 505(7484), 464-464 (2014-01-24)
E J Pappert et al.
Neurology, 47(4), 1037-1042 (1996-10-01)
To determine if ventricular cerebrospinal fluid (vCSF) alpha-tocopherol levels in Parkinson's disease (PD) patients can be increased by oral alpha-tocopherol supplementation and whether vCSF levels are linearly related to plasma alpha-tocopherol levels. In spite of its putative neuroprotective properties, alpha-tocopherol
Tahir Rafique et al.
Water environment research : a research publication of the Water Environment Federation, 85(7), 579-586 (2013-08-16)
The role of seawater dilution, along with other water-quality components, has been studied to determine the causes of spatial distribution of high fluoride concentrations in the groundwater of the Diplo sub-district, Thar Desert, Pakistan. Fluoride ion concentration ranges of up
C Syburra et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 71(3), 112-115 (1999-12-28)
It is well known that brain and nervous system cells are prone to oxidative damage because of their relatively low content of antioxidants, especially enzymatic ones, and of the high levels of both membrane polyunsaturated fatty acids (PUFA) and iron
Johanna Schmitz et al.
Biochimica et biophysica acta, 1828(9), 2032-2040 (2013-06-05)
Membrane proteins of the Arabidopsis thaliana MRS2 (MGT) family have been characterised as magnesium transporters. Like their bacterial CorA homologues, the plant MRS2 proteins are characterised by an invariable GMN tripeptide motif terminating the first of two closely spaced transmembrane
J-M Serot et al.
Journal of neurology, neurosurgery, and psychiatry, 76(11), 1585-1587 (2005-10-18)
Homocysteine may be involved in the pathogenesis of late onset Alzheimer's disease. It is implicated in the metabolism of several important pathways in the brain. Methylmalonic acid (MMA) is related to the metabolism of branched chained amino acids and fatty
Adam Drewnowski et al.
The American journal of clinical nutrition, 99(5 Suppl), 1223S-1228S (2014-03-22)
Nutrient profiling is the technique of rating or classifying foods on the basis of their nutritional value. Foods that supply relatively more nutrients than calories are defined as nutrient dense. Nutrient profile models calculate the content of key nutrients per
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