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Chen-Hsu Wang et al.
Pharmaceutical biology, 52(11), 1451-1459 (2014-07-16)
Abstract Background: Carbamazepine, which was developed primarily for the treatment of epilepsy, is now also useful for the treatment of non-epileptic disorders and inflammatory hyperalgesia. However, the mechanism of its anti-neuroinflammatory action remains poorly understood. This study elucidates the anti-neuroinflammatory
Chih-Cheng Hsiao et al.
Cancer letters, 368(1), 144-152 (2015-08-16)
Toll-like receptor-4 (TLR4) is known to influence growth and migration of hepatocellular tumors; however, its role in hepatoblastoma remains poorly understood. This study investigated the regulatory role of TLR4 in proliferation and chemoresistance of HepG2 hepatoblastoma cells. Treatment with lipopolysaccharide
Luis O'mar Serrano Figueroa et al.
Extremophiles : life under extreme conditions, 19(6), 1183-1192 (2015-10-07)
Soap Lake, located in Washington State, is a naturally occurring saline and alkaline lake. Several organisms inhabiting this lake have been identified as producers of siderophores that are unique in structure. Bacterial isolates, enriched from Soap Lake sediment and water
Vinod Vellora Thekkae Padil et al.
Journal of agricultural and food chemistry, 63(14), 3757-3765 (2015-03-24)
Esterifications of the tree-based gum, gum karaya (GK), using dodecenylsuccinic anhydride (DDSA) were carried out in aqueous solutions. GK was deacetylated using alkali treatment to obtain deacetylated gum karaya (DGK). The DGK and its DDSA derivative were characterized using gel
Chun Kiang Chua et al.
Small (Weinheim an der Bergstrasse, Germany), 11(11), 1266-1272 (2014-10-22)
Graphite oxide (GiO) and graphene oxide (GeO) possess wide applicability in technological devices. The exact chemical compositions, structures, and properties of these materials remain vague to the graphene community despite being heavily researched. As metastable materials, the properties of GiO
Embriette R Hyde et al.
Free radical biology & medicine, 77, 249-257 (2014-10-12)
The nitrate-nitrite-NO pathway to nitric oxide (NO) production is a symbiotic pathway in mammals that is dependent on nitrate reducing oral commensal bacteria. Studies suggest that by contributing NO to the mammalian host, the oral microbiome helps maintain cardiovascular health.
Jinjin Wu et al.
Environmental research, 138, 67-73 (2015-02-24)
Silver nanoparticles (Ag-NPs) are among the most commonly used nanomaterials and may be exposed to human and ecosystem. Prior in vitro study showed that Ag-NPs compromised neurodevelopment of PC12 cells. This study aims to investigate the effect of prenatal exposure
Ibrahim Yazji et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(23), 9451-9456 (2013-05-08)
Necrotizing enterocolitis (NEC) is a devastating disease of premature infants characterized by severe intestinal necrosis and for which breast milk represents the most effective protective strategy. Previous studies have revealed a critical role for the lipopolysaccharide receptor toll-like receptor 4
Yongjuan Chen et al.
PloS one, 10(1), e0113426-e0113426 (2015-01-21)
Zirconium (Zr) is an element commonly used in dental and orthopedic implants either as zirconia (ZrO2) or in metal alloys. It can also be incorporated into calcium silicate-based ceramics. However, the effects of in vitro culture of human osteoblasts (HOBs)
Josephine Selvaraj et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 15(10), 2010-2018 (2014-07-01)
Nitrogen (N)-doped reduced graphene oxide (nRGO) is systematically incorporated into a TiO(2) -CdS photoelectrochemical (PEC) cell and its role is examined in the three main components of the cell: 1) the CdS-sensitized TiO(2) photoanode, 2) the cathode, and 3) the
Pamela Allan et al.
Journal of pharmaceutical and biomedical analysis, 76, 28-35 (2013-01-08)
A 785nm diode laser and probe with a 6mm spot size were used to obtain spectra of stationary powders and powders mixing at 50rpm in a high shear convective blender. Two methods of assessing the effect of particle characteristics on
Anna-Maria Georgoudaki et al.
Immunology and cell biology, 93(6), 581-590 (2015-02-04)
Signaling lymphocytic activation molecule (SLAM) receptors have an important role in the development of immune responses because of their roles, for exampe, in NK cell cytotoxicity and cytokine production by NK, T cells and myeloid cells. The SLAM receptor CD244
Alok Rout et al.
Dalton transactions (Cambridge, England : 2003), 44(3), 1379-1387 (2014-11-26)
Trivalent rare-earth ions were extracted from nitric acid medium by the neutral phosphine oxide extractant Cyanex 923 into ionic liquid phases containing the bis(trifluoromethylsulfonyl)imide anion. Five different cations were considered: 1-butyl-3-methylimidazolium, 1-decyl-3-methylimidazolium, methyltributylammonium, methyltrioctylammonium and trihexyl(tetradecyl)phosphonium. The extraction behavior of
Pellegrino Conte
Magnetic resonance in chemistry : MRC, 53(9), 711-718 (2014-10-31)
Aqueous salt solutions play an important role in nature because of their effects on environmental biogeochemical processes and on structural properties of biomolecules. Upon dissolution, salts split in ions that are solvated. Water in hydration shells is subjected to molecular
Ching-Wei Tung et al.
Nature communications, 6, 8106-8106 (2015-09-01)
Electrochemically converting water into oxygen/hydrogen gas is ideal for high-density renewable energy storage in which robust electrocatalysts for efficient oxygen evolution play crucial roles. To date, however, electrocatalysts with long-term stability have remained elusive. Here we report that single-crystal Co3O4
Hongje Jang et al.
Advanced healthcare materials, 4(12), 1833-1840 (2015-06-19)
Herein, hybrid nanocomposite of praseodymium doped TiO2 nanocrystals and graphene oxide nanosheets are prepared by facile hydrothermal treatment. As-synthesized Pr-TiO2 /NGO hybrid nanocomposite exhibits enhanced photocatalytic activity under visible light irradiation by the intact graphene oxide and doped lanthanide mediated
Michael D Nelson et al.
The Journal of physiology, 593(23), 5183-5200 (2015-10-07)
Becker muscular dystrophy (BMD) is a progressive X-linked muscle wasting disease for which there is no treatment. BMD is caused by in-frame mutations in the gene encoding dystrophin, a structural cytoskeletal protein that also targets other proteins to the sarcolemma.
Tihitinna Asmellash Belay et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 72(6), 960-965 (2015-09-12)
Although zero-valent iron represents a promising approach for reduction of nitrate (NO(3)(-)) in water, its application in concentrated nitrate is limited by surface passivation. In this study, an alternative approach using in situ synthesized zero-valent copper (Cu(0)) produced by borohydride
Bin Wu et al.
Marine drugs, 13(8), 4617-4632 (2015-08-01)
An unusual polyketide with a new carbon skeleton, lindgomycin (1), and the recently described ascosetin (2) were extracted from mycelia and culture broth of different Lindgomycetaceae strains, which were isolated from a sponge of the Kiel Fjord in the Baltic
Xun Yuan et al.
The Analyst, 137(19), 4516-4523 (2012-08-15)
A new strategy was explored for the visual determination of Cu(2+) using copper-catalysed in situ formation of Ag nanoparticles. In this method, only common reagents were used and the pre-synthesis and modification of nanoparticles are avoided. Ag(+) can form a
X Wang et al.
Physical chemistry chemical physics : PCCP, 17(28), 18524-18534 (2015-06-26)
Metallic biomaterials are widely used to replace and/or restore the function of damaged bodily parts. The use of silver as antibacterial coatings onto implants has recently gained large interest in medical applications. The extent of silver that can be released
Daniel Lozano-Ojalvo et al.
International journal of food microbiology, 166(2), 263-269 (2013-08-27)
Most strains of Aspergillus parasiticus are able to produce high concentrations of aflatoxin (AF) B1 and G1 which are among the most potent mutagenic, teratogenic, and carcinogenic mycotoxins. Molecular studies in relation to activity of secondary metabolite gene clusters are
Adriano Ambrosi et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 16(2), 331-334 (2014-11-19)
Graphene-related materials contain chemically bonded oxygen atoms in the form of epoxy, hydroxy, carboxy, and carbonyl groups. It is important to determine the quantity of oxygen atoms and to understand their position on the graphene sheet. However, visualization of these
Raúl Bescós et al.
Medicine and science in sports and exercise, 44(12), 2400-2409 (2012-07-20)
Supplementation with inorganic nitrate has been suggested to be an ergogenic aid for athletes as nitric oxide donor. The purpose of this study was to determine whether ingestion of inorganic sodium nitrate benefits well-trained athletes performing a 40-min exercise test
Cheng-Ming Tsao et al.
Critical care (London, England), 18(6), 652-652 (2014-11-30)
The aim of this study was to investigate the effects of levosimendan on rodent septic shock induced by cecal ligation and puncture (CLP). Three hours after peritonitis-induced sepsis, male Wistar rats were randomly assigned to receive an intravenous infusion of
Maryam Ezoddin et al.
Environmental technology, 35(17-20), 2401-2409 (2014-08-26)
A microextraction method based on ultrasound-assisted surfactant-enhanced emulsification using solidification of a floating organic droplet (UASEME-SFO) was evaluated for simultaneous determination of Cd and Ni in water and tea samples followed by flame atomic absorption spectrometry. In the UASEME-SFO technique
Daryoush Afzali et al.
Journal of chromatography. A, 1247, 35-41 (2012-06-08)
In the present study, a new approach which uses immunoaffinity column clean-up combined with dispersive liquid-liquid microextraction (DLLME) is proposed for the preconcentration of ultra trace amounts of aflatoxins (B₁, B₂, G₁ and G₂). The aflatoxins are then determined using
Wei-Yang Ooi et al.
Journal of colloid and interface science, 374(1), 315-320 (2012-03-06)
Poly(N-isopropylacrylamide) (PNIPAAm) grafted with single-stranded (ss) DNA conjugate (PNIPAAm-g-DNA) self-assembles above its lower critical solution temperature to form colloidal particles. When the ssDNA within the particle hybridizes with its complementary DNA, the particles aggregate above a certain threshold of salt
Min-Yu Chung et al.
Journal of medicinal food, 18(11), 1198-1206 (2015-04-04)
A number of compounds isolated from mushrooms have exhibited disease-modifying effects. We sought to investigate the mechanisms responsible for the anti-inflammatory effects of an extract from the mushroom species Sarcodon asparatus (SAE). Male BALB/c mice (N=42; 6 weeks old) were
Geraldine Mulley et al.
PloS one, 9(4), e94409-e94409 (2014-04-15)
There has been a recent surge in the use of silver as an antimicrobial agent in a wide range of domestic and clinical products, intended to prevent or treat bacterial infections and reduce bacterial colonization of surfaces. It has been
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