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化学处理的重组胰蛋白酶在蛋白质组学和蛋白质表征分析中的应用评测
化学处理的重组胰蛋白酶在蛋白质组学和蛋白质表征分析中的应用评测
Mass Spectrometric Approaches to Lipidomic Studies
Dr. Robert Murphy, professor at University of Colorado - Denver, discusses Mass Spectrometric Approaches to Lipidomic Studies.
Mass Spectrometric Quantitation in Lipidomic Studies
Dr. Robert Murphy, professor at University of Colorado - Denver, discusses Mass Spectrometric Quantitation in Lipidomic Studies.
Ion Chromatography for Sugar Testing in Food and Environmental Analysis
In this article we demonstrate how well ion chromatography is suited as an analytical technique for sugar analysis e.g. in apple juice, milk, and dust samples.
Rapid Trypsin Digestion of Complex Protein Mixtures for Proteomics Analysis
Reliable and reproducible results in mass spectrometry proteomics analyses are highly dependent on robust sample preparation.
Quantification of Host Cell Proteins
Residual presence of host cell proteins (HCPs) in recombinant therapeutic products has considerable clinical safety risks associated with a potential immunological response in patients.
A Rapid, Streamlined Workflow for Glycan Sample Preparation and Analysis by LC-MS
The use of PNGase Fast denaturing buffer and enzyme yielded results similar to a conventional 20-hour protocol with overnight digest while reducing workflow time to about 1 hour with a 15-minute digest.
NMR Analysis of Glycans
Nuclear magnetic resonance (NMR) spectroscopy measures the extent to which a glycan or other molecule distorts a magnetic field.
Methods and Matrices for Mass Spectrometry of Glycans
Glycosylation is known to have profound influence on various physiochemical, cellular and biological functions of proteins. Alterations in this modification are known to affect the immune system and have been associated with various pathological states such as cancer, rheumatoid arthritis
Chymotrypsin
Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.
AQUA™ Peptides for Absolute Quantitation
AQUA Protein - Ordering Page
Three Methods for Critical Quality Attribute Determination of Monoclonal Antibodies
Step-by-step workflows for the intact mass analysis, peptide mapping, and N-glycan analysis of the monoclonal antibody― adalimumab, for an accurate characterization of the critical quality attributes (CQAs) to ensure drug safety and efficacy. Read more.
Quantification of Infliximab in Human Serum by LC-MS/MS Using A Full-Length Stable Isotope Labeled Internal Standard
Infliximab, a chimeric monoclonal antibody, is used to treat rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, and other autoimmune diseases.
Development of a Simple and Rapid Digestion Protocol for Proteomics Sample Preparation
In this study, we developed a rapid trypsin digest kit that, at elevated temperatures, yielded reliable, reproducible results in less than 2 hours on a wide variety of substrates for mass spectrometry.
Absolute Quantification of Serum Proteome
Absolute Quantification (Protein-AQUA™™) is a targeted quantitative proteomics technique that exhibits robust efficacy and is being increasingly utilized for a wide variety of quantitative proteomics studies.
Method Optimization for LC-MS Analysis of Vitamin D Metabolite Critical Pairs in Serum
Using HybridSPE-Phospholipid, Ascentis Express, and Other LC-MS Workflow Components