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M Corzo-Martínez et al.
Pharmaceutical research, 32(3), 1055-1071 (2014-10-02)
The aim of this work was to develop a milk-based powder formulation appropriate for pediatric delivery of ritonavir (RIT). Ultra-high pressure homogenization (UHPH) at 0.1, 300 and 500 MPa was used to process a dispersion of pasteurized skim milk (SM)...
Meghavi N Patel et al.
AAPS PharmSciTech, 15(6), 1498-1508 (2014-07-19)
The aim of this research was to advance solid lipid nanoparticle (SLN) preparation methodology by preparing glyceryl monostearate (GMS) nanoparticles using a temperature-modulated solidification process. The technique was reproducible and prepared nanoparticles without the need of organic solvents. An anticancer...
A G Schauss
Renal failure, 13(1), 1-4 (1991-01-01)
Acute renal failure (ARF) or renal dysfunction (RD) associated with germanium-induced nephrotoxicity has been reported in 18 patients since 1982. In 2 of these cases the patients died of acute renal and cardiogenic failure. In 17 of 18 cases biopsies...
Katrin Loeschner et al.
Analytical and bioanalytical chemistry, 407(16), 4541-4554 (2015-04-16)
Hip replacements are used to improve the quality of life of people with orthopaedic conditions, but the use of metal-on-metal (MoM) arthroplasty has led to poor outcomes for some patients. These problems are related to the generation of micro- to...
Racheal O Ogbodu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 149, 231-239 (2015-05-13)
The photophysical properties of the conjugate of uridine and zinc mono carboxy phenoxy phthalocyanine (ZnMCPPc-uridine, 4) are reported in this work. The conjugate was also adsorbed onto single walled carbon nanotubes (ZnMCPPc-uridine-SWCNT, 5). The X-ray photoelectron spectroscopy of 4 showed...
John Metyko et al.
Health physics, 107(5 Suppl 3), S177-S180 (2014-10-02)
Three different 90Y internally administered radionuclide therapies are currently used in both standard-of-care and clinical trial procedures atMD Anderson Cancer Center. TheraSphere and SIR-Spheres therapies utilize 90Y-labeled microspheres, while Zevalin is an 90Y-labeled radioimmunotherapeutic agent. Several publications have indicated radionuclidic...
Zhiwen Chen et al.
Journal of nanoscience and nanotechnology, 14(2), 1318-1337 (2014-04-23)
Germanium materials are a class of unique semiconductor materials with widespread technological applications because of their valuable semiconducting, electrical, optical, and thermoelectric power properties in the fields of macro/mesoscopic materials and micro/nanodevices. In this review, we describe the efforts toward...
Marilyn Tremblay et al.
Health physics, 107(6), 564-569 (2014-10-30)
The Human Monitoring Laboratory (Canada) has looked at parameters (lung volume, lung deposition pattern, etc.) that can affect the counting efficiency of its lung counting system. The calibration of the system is performed using the Lawrence Livermore National Laboratory (LLNL)...
Yunfei Jiang et al.
Plant, cell & environment, 38(11), 2387-2397 (2015-06-18)
Pea (Pisum sativum L.) is a major legume crop grown in a semi-arid climate in Western Canada, where heat stress affects pollination, seed set and yield. Seed set and pod growth characteristics, along with in vitro percentage pollen germination, pollen...
S H Tao et al.
Regulatory toxicology and pharmacology : RTP, 25(3), 211-219 (1997-06-01)
Germanium-containing dietary supplements became popular in the 1970s in Japan and later in other countries, as elixirs for certain diseases (e.g., cancer and AIDS). Germanium is not an essential element. Its acute toxicity is low. However, at least 31 reported...
Yuanyuan Yue et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 71, 244-253 (2014-07-06)
Phthalate plasticizers have been subjected to close scrutiny and evidences of their toxicity and other negative environmental impacts have arisen as a result of their use in food in some countries. Once entering human body, plasticizers could affect the conformation...
Godfred Odame Duodu et al.
Analytica chimica acta, 898, 19-27 (2015-11-04)
Wet-milling protocol was employed to produce pressed powder tablets with excellent cohesion and homogeneity suitable for laser ablation (LA) analysis of volatile and refractive elements in sediment. The influence of sample preparation on analytical performance was also investigated, including sample...
[Advances in the research of germanium].
X R Kong
Sheng li ke xue jin zhan [Progress in physiology], 27(2), 173-175 (1996-04-01)
T Matsusaka et al.
Clinical nephrology, 30(6), 341-345 (1988-12-01)
We report two cases of renal failure following long-term ingestion of germanium dioxide (GeO2) and comment on eight other cases reported in Japan. Ge-induced nephropathy is characterized by insidious onset of renal failure without proteinuria or hematuria after oral intake...
Yang Chen et al.
Journal of AOAC International, 97(4), 1143-1150 (2014-08-26)
A proficiency test (PT) program for determination of total As in apple juice samples was conducted by the Food Emergency Response Network (FERN) laboratories. An analytical method using inductively coupled plasma (ICP)-MS was validated for this project. The LOD and...
Li Z Pei et al.
Recent patents on nanotechnology, 6(1), 44-59 (2011-10-26)
Ge nanowires exhibit wide application potential in the fields of nanoscale devices due to their excellently optical and electrical properties. This article reviews the recent progress and patents of Ge nanowires. The recent progress and patents for the synthesis of...
Gui-Di Yang et al.
Ecotoxicology and environmental safety, 120, 7-12 (2015-05-31)
Arsenite [As (III)] oxidation can be accelerated by bacterial catalysis, but the effects of the accelerated oxidation on arsenic toxicity and translocation in rice plants are poorly understood. Herein we investigated how an arsenite-oxidizing bacterium, namely Brevibacillus laterosporus, influences As...
Liqun Zhou et al.
Journal of dentistry, 43(8), 973-980 (2015-06-10)
The present study examined (1) the chemical interaction between three self-etching adhesives and sodium hypochlorite (NaOCl)-deproteinised dentine, and (2) the influence of NaOCl treatment on bond strength of self-etching adhesives with/without adhesive functional monomers to dentine. Caries-free dentine disks (control)...
[Evaluation of health promotive effect of organometallic germanium compounds].
Y L Wang
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 28(6), 372-374 (1994-11-01)
Lingshang Lin et al.
Carbohydrate polymers, 134, 448-457 (2015-10-03)
Lotus rhizome C-type starch was separated into different size fractions. Starch morphologies changed from irregular to elongated, ellipsoid, oval, and spherical with decreasing granule size. The small- and very-small-sized fractions had a centric hilum, and the other size fractions had...
Jun Huang et al.
International journal of biological macromolecules, 78, 165-172 (2015-04-15)
Starches were isolated from rhizomes of Curcuma longa, Canna edulis and Canna indica and bulbs of Lilium lancifolium, and showed a B-type X-ray diffraction pattern. Their physicochemical properties were investigated and compared. These starches showed significantly different granule morphologies and...
G B Gerber et al.
Mutation research, 387(3), 141-146 (1998-01-24)
The metalloid germanium has found widespread application in electronics, nuclear sciences and in medicine. General toxicity of germanium is low, except for the tetrahydride germane, and few observations on toxicity of germanium in man exist. Germanium is not carcinogenic and...
Johannes Becker et al.
Journal of biomedical materials research. Part A, 103(8), 2549-2557 (2014-12-17)
In tissue engineering, development of an osteoconductive construct that integrates with host tissue remains a challenge. In this work, the effect of bone-like minerals on maturation of pre-osteoblast cells was investigated using polymer-mineral scaffolds composed of poly(propylene fumarate)-co-poly(caprolactone) (PPF-co-PCL) and...
A Takeuchi et al.
Nephron, 60(4), 436-442 (1992-01-01)
A 55-year-old woman was admitted to our hospital, complaining of general malaise, muscular weakness, anorexia and weight loss. She had a history of ingesting of a certain germanium (Ge) compound over the preceding 19 months, with a total dose of...
R M Slawson et al.
Plasmid, 27(1), 72-79 (1992-01-01)
Germanium is an inert metal with no known biological function in prokaryotic or eukaryotic organisms. Its toxicity is low compared to that of silver. Germanium is accumulated in certain bacterial strains by either energy-independent passive binding or an energy-dependent mechanism....
Rackel Reis et al.
ACS applied materials & interfaces, 7(27), 14644-14653 (2015-06-18)
Thin-film composite membranes, primarily based on poly(amide) (PA) semipermeable materials, are nowadays the dominant technology used in pressure driven water desalination systems. Despite offering superior water permeation and salt selectivity, their surface properties, such as their charge and roughness, cannot...
M Iijima et al.
No to shinkei = Brain and nerve, 42(9), 851-856 (1990-09-01)
A 51-year-old man, taking beverage containing inorganic germanium (Ge), (90-100 mg/day, total 70 g) for two years, developed body weight loss, anemia, renal dysfunction, peripheral neuropathy, myopathy, autonomic dysfunctions and multiple cranial nerve palsies. Serum CK, GOT, LDH, BUN, and...
Yang Yang et al.
Environmental science & technology, 48(20), 12362-12369 (2014-09-16)
Disinfectants inactivate pathogens in source water; however, they also react with organic matter and bromide/iodide to form disinfection byproducts (DBPs). Although only a few DBP classes have been systematically analyzed for toxicity, iodinated and brominated DBPs tend to be the...
Aline Girod et al.
Forensic science international, 254, 185-196 (2015-08-10)
This study investigated fingermark residues using Fourier transform infrared microscopy (μ-FTIR) in order to obtain fundamental information about the marks' initial composition and aging kinetics. This knowledge would be an asset for fundamental research on fingermarks, such as for dating...
Silvie Svarcová et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 132, 514-525 (2014-06-04)
An unambiguous identification of pigments in paint layers of works of art forms a substantial part of the description of a painting technique, which is essential for the evaluation of the work of art including determination of the period and/or...
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