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Catherine F M Bowden et al.
Biochemistry, 53(14), 2286-2294 (2014-03-22)
The Isd (iron-regulated surface determinant) system is a multiprotein transporter that allows bacterium Staphylococcus aureus to take up iron from hemoglobin (Hb) during human infection. In this system, IsdB is a cell wall-anchored surface protein that contains two near iron
Céline Termote et al.
Food and nutrition bulletin, 35(4), 458-479 (2015-02-03)
Wild foods and their actual and potential contributions to nutrition security have rarely been studied or considered in nutrition and conservation programs. To study the role of wild food biodiversity in achieving a cost reduction of a nutritionally adequate diet
Oliver M Theusinger
Praxis, 103(21), 1257-1262 (2014-10-12)
Blood transfusions are in general considered as lifesaving. Current data and evidence show, that blood transfusions are associated with increased morbidity and mortality, and this apparently dose-dependent. Basic research and results from randomized controlled trials show a causal relationship between
Shuichi Sekine et al.
Toxicology and applied pharmacology, 282(3), 237-243 (2014-12-30)
Patients with long-lasting hepatitis C virus (HCV) infection are at major risk of hepatocellular carcinoma (HCC). Iron accumulation in the livers of these patients is thought to exacerbate conditions of oxidative stress. Transgenic mice that express the HCV core protein
Crystal D Karakochuk et al.
The Journal of nutrition, 145(1), 134-142 (2014-12-21)
Anemia is common in Cambodian women. Potential causes include micronutrient deficiencies, genetic hemoglobin disorders, inflammation, and disease. We aimed to investigate factors associated with anemia (low hemoglobin concentration) in rural Cambodian women (18-45 y) and to investigate the relations between
Response to comment on "Intestinal inflammation modulates expression of the iron-regulating hormone hepcidin depending on erythropoietic activity and the commensal microbiota".
Bobby J Cherayil
Journal of immunology (Baltimore, Md. : 1950), 193(12), 5763-5763 (2014-12-07)
Maria Wilhelm et al.
Clinical nephrology, 81(4), 251-258 (2014-03-25)
Hyperphosphatemia in advanced chronic kidney disease (CKD) necessitates the use of phosphate binders. This in vitro study assessed phosphate binding and Fe release properties of the novel iron-based phosphate binder PA21. Phosphate adsorption and Fe release were assessed under conditions
Evelyn Yamal-Turbay et al.
Environmental technology, 35(13-16), 1695-1701 (2014-06-25)
Despite being acknowledged as an emerging contaminant, sulphamethazine (SMT) degradation has received scarce attention in the advanced oxidation processes field. Thus, this work addresses the degradation of SMT in water solutions (12 L of 25mgL-1 samples) by means of a
Yukio Miyamoto et al.
AJR. American journal of roentgenology, 202(4), W400-W407 (2014-03-26)
The objective of our study was to compare the efficacy of contrast-enhanced ultrasound (CEUS) using the ultrasound contrast agent Sonazoid (perflubutane) with unenhanced ultrasound and supplementary contrast-enhanced MRI in the differential diagnosis (benign vs malignant) of focal breast lesions. The
Wentao Zhang et al.
Biochemical and biophysical research communications, 455(3-4), 312-317 (2014-12-03)
Serine/arginine-rich (SR) proteins are important splicing factors. However, the biological functions of plant SR proteins remain unclear especially in abiotic stresses. Cadmium (Cd) is a non-essential element that negatively affects plant growth and development. In this study, we provided clear
Mary K Sherwood et al.
Chemosphere, 113, 56-61 (2014-07-30)
Modified Fenton (MF) chemistry was tested in the laboratory to treat three diesel fuel-contaminated soils from the Canadian arctic rich in soil organic matter (SOM) and Fe oxides. Reactors were dosed with hydrogen peroxide (HP), and treatment was compared in
Koichiro Uto et al.
Journal of nanoscience and nanotechnology, 14(4), 3193-3201 (2014-04-17)
(Apo)ferritins are cage-shaped proteins which have recently received a great deal of attention because the inner cavity of the protein shell can be used as a size-restricted reaction field for the synthesis of nanomaterials. The biomineralization behavior and inorganic nanoparticle
Sandra Isabel Escobar-Megchún et al.
Journal of water and health, 12(4), 722-726 (2014-12-05)
This study relates to a method for evaluating the degradation efficiency of Ascaris lumbricoides eggs through a Fenton reaction, using hydrogen peroxide (H2O2) at 100, 250, and 500 mg/L, ferrous sulfate (FeSO4) at 458 mg/L Fe(2+) and pH values of
Jun-Won Jang et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 59(12), 2503-2507 (2009-06-23)
Zero valent iron has been successfully used for the degradation of a wide range of contaminants. However, this reaction of using ZVI particle produces a large quantity of iron sludge. To solve the problem, we report the synthesis of self-organized
Lucie Y Guo et al.
Experimental eye research, 129, 31-37 (2014-12-03)
Age-related macular degeneration (AMD) is the most common cause of blindness among older adults in developed countries, and retinal iron accumulation may exacerbate the disease. Iron can upregulate the production of amyloid precursor protein (APP). Since amyloid-β (Aβ), a byproduct
Vivek Kumar Srivastava et al.
The Biochemical journal, 463(1), 103-114 (2014-07-06)
Iron is an essential nutrient for all living organisms and human pathogens employ a battery of factors to scavenge iron from the high-affinity iron-binding host proteins. In the present study, we have elucidated, via a candidate gene approach, major iron
The role of intravenous iron for the treatment of restless legs syndrome.
Michael Auerbach
American journal of hematology, 89(10), 1016-1016 (2014-08-05)
Non-intravenous approaches to iron therapy in chronic kidney disease: will it improve the benefit-to-risk ratio?
Anatole Besarab
Nephrology news & issues, 28(2), 12-12 (2014-03-22)
S J Ford et al.
Annals of the Royal College of Surgeons of England, 96(4), 275-278 (2014-05-02)
The incidence of oesophageal adenocarcinoma (OAC) is rising dramatically and overall survival remains extremely poor. Iron has been shown to potentiate tumourigenesis in OAC, and iron chelation therapy demonstrates promise in vivo as an adjunct to neoadjuvant and palliative chemotherapy.
Oriana Marques et al.
Cancer letters, 347(1), 1-14 (2014-02-04)
Iron is an essential element and a critical component of molecules involved in energy production, cell cycle and intermediate metabolism. However, the same characteristic chemistry that makes it so biologically versatile may lead to iron-associated toxicity as a consequence of
Antonino Missineo et al.
Infection and immunity, 82(6), 2448-2459 (2014-04-02)
Staphylococcus lugdunensis is a coagulase-negative staphylococcus that is a commensal of humans and an opportunistic pathogen. It can cause a spectrum of infections, including those that are associated with the ability to form biofilm, such as occurs with endocarditis or
Microcytic anemia.
Thomas G DeLoughery
The New England journal of medicine, 371(14), 1324-1331 (2014-10-02)
Angelo Belotti et al.
Leukemia research, 39(1), 88-91 (2014-12-02)
We analyzed appearance of non transferrin bound iron (NTBI) in 30 transplant eligible patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) during conventional chemotherapy treatment program and evaluated possible relationship with transfusional body iron intake, iron parameters
Yingxun Liu et al.
Journal of biomedical nanotechnology, 10(8), 1574-1587 (2014-07-16)
To evaluate the effects of iron oxide nanoparticles on genes from different cell lines in this study, mouse macrophage RAW264.7 and hepatocyte Hepa1-6 cell lines were treated with DMSA-coated Fe3O4 nanoparticles. Two doses were used, 50 microg/mL and 100 microg/mL
Biochemistry. Fishing for peroxidase protons.
John T Groves et al.
Science (New York, N.Y.), 345(6193), 142-143 (2014-07-12)
Julia Steuber et al.
Nature, 516(7529), 62-67 (2014-12-05)
NADH oxidation in the respiratory chain is coupled to ion translocation across the membrane to build up an electrochemical gradient. The sodium-translocating NADH:quinone oxidoreductase (Na(+)-NQR), a membrane protein complex widespread among pathogenic bacteria, consists of six subunits, NqrA, B, C
Xuechao Guo et al.
Chemosphere, 112, 1-8 (2014-07-23)
Iron (Fe) has been widely applied to treat arsenic (As)-contaminated water, and Fe could influence bioavailability and toxicity of As. However, little is known about the impact of As and/or Fe on gut microbiota, which plays important roles in host
Ahmad Al-As'ad et al.
Environmental technology, 35(13-16), 1630-1638 (2014-06-25)
The use of coagulation and Fenton oxidation was studied for total organic carbon (TOC) and silica removal from steam-assisted gravity drainage (SAGD) water at 800C and two different concentrations replicating the stream feeding the warm lime softening unit having 675
Roberta J Ward et al.
The Lancet. Neurology, 13(10), 1045-1060 (2014-09-19)
In the CNS, iron in several proteins is involved in many important processes such as oxygen transportation, oxidative phosphorylation, myelin production, and the synthesis and metabolism of neurotransmitters. Abnormal iron homoeostasis can induce cellular damage through hydroxyl radical production, which
David Z Mokry et al.
Biochimica et biophysica acta, 1840(10), 3058-3066 (2014-06-28)
For many pathogenic microorganisms, iron acquisition represents a significant stress during the colonization of a mammalian host. Heme is the single most abundant source of soluble iron in this environment. While the importance of iron assimilation for nearly all organisms
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