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  • Effect of a nutrient mixture on the localization of extracellular matrix proteins in HeLa human cervical cancer xenografts in female nude mice.

Effect of a nutrient mixture on the localization of extracellular matrix proteins in HeLa human cervical cancer xenografts in female nude mice.

Experimental and therapeutic medicine (2015-12-02)
M Waheed Roomi, John Cha, Tatiana Kalinovsky, Nusrath Roomi, Aleksandra Niedzwiecki, Matthias Rath
摘要

Cervical cancer is one of the most commonly diagnosed cancers and a significant cause of mortality in women worldwide. Although cervical cancer is fully treatable in the early stages, once it has metastasized, patient outcome is poor. The objective of the present study was to investigate the effect of dietary supplementation with a nutrient mixture (NM) containing lysine, ascorbic acid, proline, green tea extract and other micronutrients on the expression of extracellular matrix (ECM) proteins in HeLa cell xenografts in nude female mice. After housing for 1 week, female athymic nude mice between 5 and 6 weeks of age (n=12) were inoculated subcutaneously with 3×10

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甲醛 溶液, ACS reagent, 37 wt. % in H2O, contains 10-15% Methanol as stabilizer (to prevent polymerization)
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甲醛 溶液, for molecular biology, 36.5-38% in H2O
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甲醛 溶液, for molecular biology, BioReagent, ≥36.0% in H2O (T)
Supelco
苏木精
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苏木精, certified by the Biological Stain Commission
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甲醛 溶液, meets analytical specification of USP, ≥34.5 wt. %
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甲醛-12C 溶液, 20% in H2O, 99.9 atom % 12C