[跳转至内容](https://www.sigmaaldrich.com#main-content) [](https://www.sigmaaldrich.com/SG/zh) 产品 购物车0 SGZH 产品 产品应用服务资源支持 [登录 / 注册](https://www.sigmaaldrich.com/oidc-sign-in) [订单查询](https://www.sigmaaldrich.com/SG/zh/order-lookup) [快速订购](https://www.sigmaaldrich.com/SG/zh/quick-order) 购物车0 [Home](https://www.sigmaaldrich.com/SG/en)[Solid Phase Microextraction (SPME)](https://www.sigmaaldrich.com/SG/en/applications/analytical-chemistry/sample-preparation/solid-phase-microextraction)Introduction to SPME # Introduction to SPME [Learn More About SPME](https://www.sigmaaldrich.com/SG/en/applications/analytical-chemistry/sample-preparation/solid-phase-microextraction) Solid-phase microextraction or SPME is a unique solventless sample prep technique. SPME uses a polymer-coated fiber to concentrate volatile and semi-volatile organics in one extraction step. SPME requires no solvents or complicated extraction apparatus. The SPME fiber is attached to a plunger inside a protective needle, which is attached to a holder that looks like a micro liter syringe. The plunger inside of the holder moves the SPME fiber into and out of a protective needle for extraction of organics from a sample matrix. The organics are adsorbed onto the liquid coating on the fiber for a predetermined amount of time. The SPME fiber is retracted into the protective needle and injected into the heated injector of the gas chromatograph. The organics are then thermally transferred onto the chromatographic column for separation and measurement. Afterwards, the SPME fiber is retracted into the needle and removed from the injection port for subsequent sample analysis. __Related Articles__ - [Biodiesel](https://www.sigmaaldrich.com/SG/en/technical-documents/technical-article/analytical-chemistry/gas-chromatography/biodiesel) - [Automated Solid Phase Microextraction (SPME) Sampling](https://www.sigmaaldrich.com/SG/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/automated-spme-sampling) - [Bioanalysis with SPME](https://www.sigmaaldrich.com/SG/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/bioanalysis-with-spme) - [BioSPME for Plasma Protein Binding Assay: Details of Method Development and Optimization](https://www.sigmaaldrich.com/SG/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/biospme-plasma-protein-binding-assay) - [Solid Phase Microextraction: Frequently Asked Questions](https://www.sigmaaldrich.com/SG/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/faq) - [GC/MS/MS Analysis of BPA in Energy Drink](https://www.sigmaaldrich.com/SG/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/gc-ms-ms-analysis-of-bisphenol-a-bpa-in-a-fruit-flavored-energy-drink-cla010218a) - [Rugged SPME Sampling](https://www.sigmaaldrich.com/SG/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/nitinol-core-spme-fibers) - [SPME Fiber Performance Tips for Volatiles & Semi-Volatiles](https://www.sigmaaldrich.com/SG/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/performance-tips) - [View More](https://www.sigmaaldrich.com/SG/en/search/facet-search?focus=sitecontent&term=facet-search) 顶部 __登录以继续。__ 如要继续阅读，请登录或创建帐户。 登录__暂无帐户？__注册 支持[客户支持](https://www.sigmaaldrich.com/SG/zh/support/customer-support)[联系我们](https://www.sigmaaldrich.com/SG/zh/collections/offices)[常见问题](https://maestro.my.site.com/knowledgeportal/s/)[安全数据表（SDS）](https://www.sigmaaldrich.com/SG/zh/documents-search?tab=sds)[证书（COA/COO）](https://www.sigmaaldrich.com/SG/zh/documents-search?tab=coa)[质量与监管](https://www.sigmaaldrich.com/SG/zh/life-science/quality-and-regulatory-management)[计算器和应用程序](https://www.sigmaaldrich.com/SG/zh/support/calculators-and-apps)[网络研讨会](https://www.sigmaaldrich.com/SG/zh/collections/webinars) 订单[快速订购](https://www.sigmaaldrich.com/SG/zh/quick-order)[定制产品](https://www.sigmaaldrich.com/SG/zh/services/custom-products)[电子商务解决方案](https://www.sigmaaldrich.com/SG/zh/life-science/ecommerce/ecommerce-solutions) 公司名称[关于我们](https://www.sigmaaldrich.com/SG/zh/life-science/about-us)[责任](https://www.sigmaaldrich.com/SG/zh/life-science/ssbi)[活动](https://www.sigmaaldrich.com/SG/zh/collections/events)[新闻发布](https://www.sigmaaldrich.com/SG/zh/collections/press)[计划](https://www.sigmaaldrich.com/SG/zh/life-science/partnership-programs)[职业生涯](https://careers.merckgroup.com/global/en)[办事处](https://www.sigmaaldrich.com/SG/zh/collections/offices) 社交媒体 [](https://www.linkedin.com/company/merck-life-science) [](https://x.com/Merck_lifesci) [](https://www.facebook.com/Merck.lifescience) [](https://www.instagram.com/mercklifescience/) [](https://www.youtube.com/@MerckLifeScience/featured) Merck __Research.开发。__ 我们是全球生命科学行业的领先供应商，为研究、生物技术开发和生产以及药物治疗开发和生产提供解决方案和服务。 [](https://www.sigmaaldrich.com/SG/zh) [Sigma-Aldrich® 溶液](https://www.sigmaaldrich.com/SG/zh/life-science/sigma-aldrich)[BioReliance® 解决方案](https://www.sigmaaldrich.com/SG/zh/life-science/bioreliance)[密理博溶液](https://www.sigmaaldrich.com/SG/zh/life-science/millipore)[SAFC® 解决方案](https://www.sigmaaldrich.com/SG/zh/life-science/safc)[Milli-Q® 解决方案](https://www.sigmaaldrich.com/SG/zh/life-science/milliq)[Supelco® 解决方案](https://www.sigmaaldrich.com/SG/zh/life-science/supelco) © 2026 Merck KGaA, Darmstadt, Germany and/or its affiliates.版权所有，包括用于人工智能培训的文本和数据挖掘以及类似技术。 未经许可，严禁复制本网站的任何资料。 [网站使用条款](https://www.sigmaaldrich.com/SG/zh/life-science/legal/site-use-terms)|[隐私政策](https://www.sigmaaldrich.com/SG/zh/life-science/legal/privacy-statement)|[一般销售条款和条件](https://www.sigmaaldrich.com/SG/zh/life-science/legal/terms-and-conditions)|[版权同意书](https://www.sigmaaldrich.com/SG/zh/life-science/legal/copyright-consent)|[网站地图](https://www.sigmaaldrich.com/SG/zh/site-map) An unknown error has occured.