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1.02066

Supelco

Calcium carbonate

precipitated for analysis EMSURE® Reag. Ph Eur

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About This Item

Linear Formula:
CaCO3
CAS Number:
Molecular Weight:
100.09
Beilstein:
8008338
MDL number:
UNSPSC Code:
12352302
EC Index Number:
207-439-9
NACRES:
NA.21

Agency

reag. Ph. Eur.

Quality Level

product line

EMSURE®

Assay

98.5-100.5% dry basis (complexometric)

form

solid

potency

6450 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)

impurities

≤0.005% Substances insoluble in hydrochloric acid
≤0.2% Substances insoluble in acetic acid

loss

≤ 1.0% loss on drying, 200 °C

particle size

~14 μm (D 50)

pH

9.5-10.5 (20 °C, 100 g/L in H2O, slurry)

mp

825 °C (decomposition)

density

2.93 g/mL at 25 °C (lit.)

bulk density

300‑1400 kg/m3

anion traces

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.03%

cation traces

Al: ≤0.005%
As: ≤0.0004%
Ba:, passes test
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.02%
Mg and allied cations: ≤1.5%
N: ≤0.001%
Na: ≤0.2%
Pb: ≤0.0005%
Sr: ≤0.1%
heavy metals (as Pb): ≤0.002%

storage temp.

10-30°C

SMILES string

[Ca++].[O-]C([O-])=O

InChI

1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2

InChI key

VTYYLEPIZMXCLO-UHFFFAOYSA-L

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Related Categories

Application


  • Comparison of passive targeted delivery of inorganic and organic nanocarriers among different types of tumors.: This study compares the efficiency of calcium carbonate-based nanocarriers in targeted drug delivery across various tumor types, offering insights into their potential for enhancing cancer treatment efficacy (Postovalova et al., 2024).


Analysis Note

Assay (complexometric; calculated on dried substance): 98.5 - 100.5 %
Identity: passes test
Substances insoluble in acetic acid: ≤ 0.2 %
Substances insoluble in hydrochloric acid: ≤ 0.005 %
Chloride (Cl): ≤ 0.005 %
Sulfate (SO₄): ≤ 0.03 %
Heavy metals (as Pb): ≤ 0.002 %
Total nitrogen (N): ≤ 0.001 %
Al (Aluminium): ≤ 0.005 %
As (Arsenic): ≤ 0.0004 %
Ba (Barium): passes test
Cu (Copper): ≤ 0.0005 %
Fe (Iron): ≤ 0.001 %
K (Potassium): ≤ 0.005 %
Mg (Magnesium): ≤ 0.02 %
Na (Sodium): ≤ 0.2 %
Pb (Lead): ≤ 0.0005 %
Sr (Strontium): ≤ 0.1 %
Magnesium and alkali metals: ≤ 1.5 %
Particle size (d 50): about 14 µm
Loss on drying (200 °C): ≤ 1.0 %
Corresponds to Reag. Ph Eur

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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