This product is sold as a primary standard. The potency of Product N1400000 is reported on a lot-specific basis on the European Pharmacopoeia (EP) document called a Leaflet or Information Leaflet. Here is the link to the EP website: https://crs.edqm.eu/db/4DCGI/View=N1400000
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100 MG
€145.00
About This Item
CAS Number:
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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Product Name
Nystatin, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
SMILES string
O[C@@H]([C@H](C)[C@H](C)O1)[C@@H](C)/C=C/C=C/CC/C=C/C=C/C=C/C=C/[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@]3([H])[C@H](C(O)=O)[C@@H](O)C[C@](O)(O3)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)C[C@@H](O)CC1=O
InChI key
VQOXZBDYSJBXMA-QEKUPDCNSA-N
grade
pharmaceutical primary standard
API family
nystatin
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
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This Item | 1477003 | N3503 | N6261 |
|---|---|---|---|
| grade pharmaceutical primary standard | grade pharmaceutical primary standard | grade - | grade - |
| manufacturer/tradename EDQM | manufacturer/tradename USP | manufacturer/tradename - | manufacturer/tradename - |
| format neat | format neat | format - | format - |
| application(s) pharmaceutical (small molecule) | application(s) pharmaceutical (small molecule) | application(s) - | application(s) - |
| API family nystatin | API family nystatin | API family - | API family - |
Application
Nystatin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
Mode of Action: Nystatin acts by binding to ergosterols in fungal cell membranes, increasing permeability of the membrane, and creating nystatin/ergosterol based ion channels. It also functions as a lipid raft-inhibiting reagent and as membrane associated cholesterol.
Antimicrobial spectrum: Nystatin acts against fungi, yeasts and molds.
Antimicrobial spectrum: Nystatin acts against fungi, yeasts and molds.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
related product
Product No.
Description
Pricing
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Santhanam Shanmughapriya et al.
Biofouling, 28(9), 929-935 (2012-09-12)
The presence of intrauterine contraceptive devices (IUDs) gives a solid surface for attachment and an ideal niche for biofilm to form and flourish. Pelvic actinomycosis is often associated with the use of IUDs. Treatment of IUD-associated pelvic actinomycosis requires the
S Giuliano et al.
Annali di igiene : medicina preventiva e di comunita, 25(1), 57-64 (2013-02-26)
The present study represents a preliminary evaluation of the impact of topical nystatin prophylaxis administration and adequate CVC management on reducing the chance of developing candidemia in neurosurgical intensive care unit (NICU) patients. We conducted a case-control study at the
Ryan F Seipke et al.
Methods in enzymology, 517, 47-70 (2012-10-23)
We describe methods used to isolate and identify antifungal compounds from actinomycete strains associated with the leaf-cutter ant Acromyrmex octospinosus. These ants use antibiotics produced by symbiotic actinomycete bacteria to protect themselves and their fungal cultivar against bacterial and fungal
Ginekologia polska, 83(12), 956-959 (2013-03-16)
The group of experts representing the Polish Gynecologic Society has issued this statement based on the review of available literature on the potential benefits of the use of Macmiror Complex 500 in obstetrical and gynecologic practice. Mixed Vaginitis (MV) eg.
Ravikumar B Shinde et al.
Annals of clinical microbiology and antimicrobials, 11, 27-27 (2012-10-06)
Biofilms formed by Candida albicans are resistant towards most of the available antifungal drugs. Therefore, infections associated with Candida biofilms are considered as a threat to immunocompromised patients. Combinatorial drug therapy may be a good strategy to combat C. albicans
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What would the conversion of this 100mg stock concentration be to Units? I'm looking to add 25 U/mL nystatin to my cell culture media (based off previous protocols) but am not sure what the conversion is.
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