PHR2355

Betaine

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Oxyneurine, Trimethylglycine, Betaine, (Carboxymethyl)trimethylammonium inner salt
• Linear Formula: (CH₃)₃N⁺CH₂COO^-
• CAS Number: 107-43-7
• Molecular Weight: 117.15
• Beilstein: 3537113
• MDL number: MFCD00012123

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Agency: traceable to USP 1065695
• form: powder
• CofA: current certificate can be downloaded
• packaging: pkg of 1000 mg
• storage temp.: 2-30°C
• SMILES string: C[N+](C)(C)CC([O-])=O
• InChI: 1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
• InChI key: KWIUHFFTVRNATP-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Biochem/physiol Actions

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC5297 in the documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable