AASS
aminoadipate-semialdehyde synthase
Synonyms:
LKR/SDH, LKRSDH, LORSDH
Species:
Human AASS (10157), Mouse Aass (30956), Rat Aass (296925), domestic cat AASS (101091272), Zebrafish aass (556229), chicken AASS (417757), domestic guinea pig Aass (100722098), naked mole-rat Aass (101707268), Horse AASS (100056260), cow AASS (520865) ...More
UniProtKB ID:
Gene ID:
- Human(10157) Summary: This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008]
- Mouse(30956) aminoadipate-semialdehyde synthase
- Rat(296925) aminoadipate-semialdehyde synthase
- domestic cat(101091272) aminoadipate-semialdehyde synthase
- Zebrafish(556229) aminoadipate-semialdehyde synthase
- chicken(417757) aminoadipate-semialdehyde synthase
- domestic guinea pig(100722098) aminoadipate-semialdehyde synthase
- naked mole-rat(101707268) aminoadipate-semialdehyde synthase
- Horse(100056260) aminoadipate-semialdehyde synthase
- cow(520865) aminoadipate-semialdehyde synthase
- sheep(101103973) aminoadipate-semialdehyde synthase
- Domestic Rabbit(100352070) aminoadipate-semialdehyde synthase
- dog(482429) aminoadipate-semialdehyde synthase
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