ASGR2
asialoglycoprotein receptor 2
Synonyms:
ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2
Species:
Human ASGR2 (433), Mouse Asgr2 (11890), Rat Asgr2 (29403), sheep ASGR2 (101115381), naked mole-rat Asgr2 (101705711), cow ASGR2 (531519), domestic cat ASGR2 (101095292), dog ASGR2 (100687999), domestic guinea pig Asgr2 (100714463)
UniProtKB ID:
Gene ID:
- Human(433) Summary: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
- Mouse(11890) asialoglycoprotein receptor 2
- Rat(29403) asialoglycoprotein receptor 2
- sheep(101115381) asialoglycoprotein receptor 2
- naked mole-rat(101705711) asialoglycoprotein receptor 2
- cow(531519) asialoglycoprotein receptor 2
- domestic cat(101095292) asialoglycoprotein receptor 2
- dog(100687999) asialoglycoprotein receptor 2
- domestic guinea pig(100714463) asialoglycoprotein receptor 2
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