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Merck

C1QA

complement component 1, q subcomponent, A chain

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(712) Summary: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. [provided by RefSeq, Jul 2008]
  • Mouse(12259) complement component 1, q subcomponent, alpha polypeptide
  • Rat(298566) complement component 1, q subcomponent, A chain
  • naked mole-rat(101703487) complement component 1, q subcomponent, A chain
  • domestic guinea pig(100724576) complement component 1, q subcomponent, A chain
  • dog(478194) complement component 1, q subcomponent, A chain
  • cow(534961) complement component 1, q subcomponent, A chain
  • sheep(101102126) complement component 1, q subcomponent, A chain
  • Zebrafish(553548) complement component 1, q subcomponent, A chain
  • chicken(419504) complement component 1, q subcomponent, A chain
  • domestic cat(101096082) complement component 1, q subcomponent, A chain

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-C1QA antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
Complement component C1q from human serum, ≥95% (SDS-PAGE),
Species
human