CASP8AP2
caspase 8 associated protein 2
Synonyms:
CED-4, FLASH, RIP25
Species:
Human CASP8AP2 (9994), Mouse Casp8ap2 (26885), Rat Casp8ap2 (313128), Horse CASP8AP2 (100065766), naked mole-rat Casp8ap2 (101700716), domestic cat CASP8AP2 (101095416), dog CASP8AP2 (481921), sheep CASP8AP2 (101109100), Domestic Rabbit CASP8AP2 (100342805), cow CASP8AP2 (505138) ...More
UniProtKB ID:
Gene ID:
- Human(9994) Summary: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
- Mouse(26885) caspase 8 associated protein 2
- Rat(313128) caspase 8 associated protein 2
- Horse(100065766) caspase 8 associated protein 2
- naked mole-rat(101700716) caspase 8 associated protein 2
- domestic cat(101095416) caspase 8 associated protein 2
- dog(481921) caspase 8 associated protein 2
- sheep(101109100) caspase 8 associated protein 2
- Domestic Rabbit(100342805) caspase 8 associated protein 2
- cow(505138) caspase 8 associated protein 2
- domestic guinea pig(100729800) caspase 8 associated protein 2
- chicken(421810) caspase 8 associated protein 2
- Zebrafish(541521) CASP8 associated protein 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-FLASH antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Small Molecule - Substrate
Product Number
Description
Species
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Species
rat, mouse, human
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,
Species
rat, mouse, human